The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government.
Read our disclaimer for details.
To investigate the validity of a clinical model to determine the relative potency of different preparations of inhaled corticosteroids used for the treatment of asthma or of eosinophilic bronchitis without asthma.
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study:
18 Years to 70 Years (Adult, Senior)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Sputum eosinophilia >3%
Adults age 18-70 years
History of episodic wheeze, chest tightness, dyspnea or cough within the last 12 months.
FEV1 ≥ 60% predicted
Steroid naive or on not more than 500 µg a day of beclomethasone or equivalent.
Able to give written informed consent
Recent asthma or COPD exacerbation (as judged by the clinician) due to respiratory infection within the last month
Relevant seasonal allergen exposure within 4 weeks or within the course of the study
Treatment with prednisone or antibiotics or hospitalisation within the past 6 weeks
Other respiratory diseases
Women who are pregnant or unwilling to use appropriate contraception during the study
Unable to withhold short-acting ß-agonist treatment for 6 hours before visit