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Vasoactive Hormones During the Night in Patients With Obstructive Sleep Apnea and Healthy Controls.

This study has been completed.
Information provided by:
Regional Hospital Holstebro Identifier:
First received: February 13, 2006
Last updated: April 17, 2008
Last verified: April 2008

Obstructive sleep apnea syndrome is complicated by considerable cardiovascular morbidity and mortality, at least partly due to hypertension. Nocturnal hypoxia, hypercapnia and acidosis stimulate chemoreceptors and presumably increased secretion of vasoactive hormones which might be responsible for hypertension in these patients.

The aim of this study is to measure the secretion of vasoactive hormones at night and to analyse the relationship between vasoactive hormones, oxygen saturation and the blood pressure at night.

Condition Phase
Healthy Obstructive Sleep Apnea Phase 4

Study Type: Observational
Study Design: Time Perspective: Prospective

Resource links provided by NLM:

Further study details as provided by Regional Hospital Holstebro:

Study Start Date: January 2004

Ages Eligible for Study:   20 Years to 65 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

Male and female Age 20-65 Obstructive sleep apnea

Exclusion Criteria:

Drug or alcohol abuse Pregnancy or breast feeding Cancer Clinical signs or history of disease in the heart, lungs, kidney or endocrine organs Abnormal laboratory tests Albuminuria or glucosuria Aterial hypertension for healthy subjects

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Please refer to this study by its identifier: NCT00291993

Department of Medical Research, Holstebro Hospital
Holstebro, Ringkoebing County, Denmark, 7500
Department of Medical Research
Holstebro, Denmark, 7500
Holstebro Hospital, Department of Medical Research
Holstebro, Denmark, 7500
Sponsors and Collaborators
Regional Hospital Holstebro
Study Chair: Erling B Pedersen, Professor Holstebro Hospital, Department of Medical Research
Principal Investigator: Pia H Hansen, MD Holstebro Hospital, Department of Medical Research
  More Information Identifier: NCT00291993     History of Changes
Other Study ID Numbers: MED.RES.HOS.2004.01.PHH
Study First Received: February 13, 2006
Last Updated: April 17, 2008

Keywords provided by Regional Hospital Holstebro:
Obstructive sleep apnea
Vasoactive hormones
Blood pressure

Additional relevant MeSH terms:
Sleep Apnea Syndromes
Sleep Apnea, Obstructive
Respiration Disorders
Respiratory Tract Diseases
Signs and Symptoms, Respiratory
Signs and Symptoms
Sleep Disorders, Intrinsic
Sleep Wake Disorders
Nervous System Diseases processed this record on August 22, 2017