Inspiratory Muscle Training in Hypercapnic COPD
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|ClinicalTrials.gov Identifier: NCT00291460|
Recruitment Status : Unknown
Verified February 2006 by Krankenhaus Kloster Grafschaft.
Recruitment status was: Recruiting
First Posted : February 14, 2006
Last Update Posted : August 21, 2006
|Condition or disease||Intervention/treatment||Phase|
|COPD Respiratory Failure||Device: inspiratory muscle training||Phase 4|
Inspiratory muscle training is known to improve inspiratory muscle strength, inspiratory muscle endurance and walking distance within six minutes in patients with neuromuscular and thoraco-restrictive disease as well as in patients with COPD. Studies have only been conducted in patients without established respiratory failure. COPD patients with respiratory failure though are characterized by higher work rates of the inspiratory muscles and higher esophageal pressure swings compared to non-hypercapnic patients indication a discrepancy between muscle load and muscle capabilities. Therefore we hypothesize that for these patients training of their inspiratory muscles will be of benefit in terms of improvement of muscular and whole body endurance.
During this investigation inspiratory muscle training will be applied in a randomized controlled fashion in 40 patients over a period of four weeks parallel to physical rehabilitation.
|Study Type :||Interventional (Clinical Trial)|
|Enrollment :||40 participants|
|Intervention Model:||Parallel Assignment|
|Official Title:||Randomized Controlled Trial of Inspiratory Muscle Training in Patients With Stable Hypercapnic Respiratory Failure Due to COPD|
|Study Start Date :||February 2006|
|Study Completion Date :||March 2008|
- inspiratory muscle strength
- inspiratory muscle endurance
- walking distance with dyspnea score
- Carbon dioxide level
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00291460
|Contact: Dominic Dellweg, M.D.||+49 2972 791 ext firstname.lastname@example.org|
|Fachkrankenhaus Kloster Grafschaft||Recruiting|
|Schmallenberg, Germany, 57392|
|Contact: Dominic Dellweg, M.D. +49 2972 ext 1257 email@example.com|
|Principal Investigator: Dominic Dellweg, M.D.|
|Sub-Investigator: Karina Reissig|
|Principal Investigator:||Dominic Dellweg, M.D.||FKKG|
|Study Chair:||Dieter Koehler, Prof. Dr.||FKKG|