Identifying Residential Hazards Using Home Test Kits

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ClinicalTrials.gov Identifier: NCT00285532

Recruitment Status : Completed

First Posted : February 2, 2006

Last Update Posted : November 18, 2014

Sponsor:

Information provided by:

National Institute of Environmental Health Sciences (NIEHS)

Study Description

Brief Summary:

The purpose of this project is to help families and communities identify and reduce health risks from lead, pesticides and, ultimately, other environmental hazards. We have partnered with the Better Housing League and Baby's Milk Fund in Cincinnati and nationally with the Alliance to End Childhood Lead Poisoning and the National Center for Lead Safe Housing. The first specific aim of this project is to evaluate a sampling kit for families to assess levels of lead and pesticides in their home environment. This aim will strengthen right-to-know laws by providing families with tools to assess environmental contamination in their own homes. The second aim is to increase community awareness of the role of environmental agents in developmental disorders, hearing loss and school problems.

Condition or disease
Poisoning, Lead

Detailed Description:

A cross-sectional random, stratified study design will be used for this project. All children who are younger than 5 years of age and have a venipuncture blood sample taken at the babies Milk Fund Clinic will be eligible for this study. After checking the lists for errors and duplications, we will randomly permute the sampling frame, stratifying on children's blood lead concentration. Stratification will be used to enroll about 33% of the sample with blood lead concentrations below 5 mg/dl, 33% between 5 to 10 mg/dl, and 33% of 10 mg/dl or higher. Stratifying the sample will improve our chances of testing the predictive validity of home sampling kits to identify children who have blood lead concentration > 10 mg/dl collected by families. In addition this study will:

Develop a pesticide wipe sampling kit to accompany our lead-sampling kit.
Evaluate the predictive validity of home sampling kits for lead-contaminated floor dust to identify children who have blood lead levels of 10 mg/dl or higher by community participants compared with repeat samples taken by trained, community workers.
Evaluate the reliability of home sampling kits for pesticides in dust collected by community participants compared with trained, community workers.
Disseminate data on the reliability of home sampling tests and provide tools for families to collect environmental samples for large, population-based studies.
Develop a Healthy Homes Resource Center at the Better Housing League to disseminate information to the community about residential hazards.

Study Design


Study Type :	Observational
Estimated Enrollment :	150 participants
Time Perspective:	Prospective
Study Start Date :	October 2001
Actual Primary Completion Date :	October 2006
Actual Study Completion Date :	October 2006

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Pesticides Poisoning

U.S. FDA Resources

Groups and Cohorts

Group/Cohort
Home test kit

Outcome Measures

Primary Outcome Measures :

Lead and Pesticide Levels [ Time Frame: One time home visit 3-5 days after distribution of kits ]

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:	3 Months to 5 Years (Child)
Sexes Eligible for Study:	All
Accepts Healthy Volunteers:	Yes
Sampling Method:	Probability Sample

Study Population

Children <5 years receiving care via Babies Milk Fund Clinics

Criteria

Inclusion Criteria:

Venous blood lead In residence 3 months Child less than 5 years of age Sampler greater than 18 years of age

Exclusion Criteria:

Cannot read or understand English Physically unable to conduct field sampling Outside of theGreater Cincinnati area

Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00285532

Locations


United States, Ohio
University of Cincinnati
Cincinnati, Ohio, United States, 45267-0056

Sponsors and Collaborators

National Institute of Environmental Health Sciences (NIEHS)

Investigators


Principal Investigator:	Sandy M Roda, BS	University of Cincinnati

More Information


ClinicalTrials.gov Identifier:	NCT00285532 History of Changes
Other Study ID Numbers:	11261-CP-002
First Posted:	February 2, 2006 Key Record Dates
Last Update Posted:	November 18, 2014
Last Verified:	November 2014

Keywords provided by National Institute of Environmental Health Sciences (NIEHS):


Blood Lead Pesticides Community-based Sampling Kits

Additional relevant MeSH terms:


Poisoning Lead Poisoning Chemically-Induced Disorders

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