Choroidal Blood Flow Response to Hand-grip Test in Progressive Glaucoma
![]() |
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. |
ClinicalTrials.gov Identifier: NCT00284440 |
Recruitment Status :
Withdrawn
(enrollment problems)
First Posted : January 31, 2006
Last Update Posted : March 10, 2015
|
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
Condition or disease |
---|
Primary Open Angle Glaucoma |
Study Type : | Observational |
Actual Enrollment : | 0 participants |
Observational Model: | Case-Only |
Time Perspective: | Prospective |
Official Title: | Relationship Between Visual Field Progression in Glaucoma and Choroidal Blood Flow Response to the Hand-grip Test |
Study Start Date : | March 2006 |
Actual Primary Completion Date : | June 2011 |
Actual Study Completion Date : | June 2011 |


Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study: | 30 Years to 80 Years (Adult, Older Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Sampling Method: | Non-Probability Sample |
Inclusion Criteria: Patients fulfilling two out of three of the following criteria in one or both eyes: a) typical glaucomatous disc, b) visual field damage (a cluster of three points (except rim points) in at least one hemifield reduced by 5 dB or greater and including at least one point reduced by 10 dB or greater; a cluster of two points reduced by 10 dB or greater; or three adjacent points on the nasal horizontal meridian that differed by 5 dB or greater from their mirror points on the opposite side of the meridian), c) intraocular pressure above 21 mm Hg at least at one occasion. Furthermore, patients need to have a series of at least 5 visual field examinations, after exclusion of the first test, for assessment of progression.
-
Exclusion Criteria:
- Ametropia > 3dpt
- Inadequate transparency of ocular media as defined by physical examination
- Iridocorneal angle extremely narrow with complete or partial closure as determined by gonioscopy
- Any abnormality which in the physician's view would prevent reliable applanation tonometry or LDF of at least one eye
- History of chronic or recurrent severe inflammatory eye disease such as scleritis or uveitis
- History of ocular trauma or intraocular surgery within the past 6 months
- History of infection or inflammation within the past 3 months
- History of clinically significant or progressive retinal disease such as retinal degeneration, diabetic retinopathy or retinal detachment
- Patients with a significant history and/or active alcohol or drug abuse (significant is defined as that which in the opinion of the investigator may either put the patient at risk because of participation in the study or may influence the results of the study or the patient's ability to participate in the study).

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00284440
Switzerland | |
University Eye Clinic | |
Basel, BS, Switzerland, 4031 |
Principal Investigator: | Selim Orguel, MD | Chief of department of diagnostics |
Responsible Party: | University Hospital, Basel, Switzerland |
ClinicalTrials.gov Identifier: | NCT00284440 |
Other Study ID Numbers: |
072-Leh-2005-001 |
First Posted: | January 31, 2006 Key Record Dates |
Last Update Posted: | March 10, 2015 |
Last Verified: | March 2015 |
Visual field progression Choroidal blood flow |
Glaucoma Glaucoma, Open-Angle Ocular Hypertension Eye Diseases |