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Improvement in Baroreflex Sensitivity in OSAS

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified May 2005 by Nagoya University.
Recruitment status was:  Recruiting
Information provided by:
Nagoya University Identifier:
First received: January 27, 2006
Last updated: NA
Last verified: May 2005
History: No changes posted
Individuals with obstructive sleep apnea syndrome (OSAS) are at high risk for cardiovascular morbidity and mortality. The effect of long-term nocturnal therapy with continuous positive airway pressure (CPAP) on daytime baroreflex sensitivity (BRS), a predictor of cardiac death, was investigated in OSAS patients.

Condition Intervention
Obstructive Sleep Apnea Syndrome Device: continuous positive airway pressure therapy

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment

Resource links provided by NLM:

Further study details as provided by Nagoya University:


Ages Eligible for Study:   20 Years to 70 Years   (Adult, Senior)
Sexes Eligible for Study:   All

Inclusion Criteria:

  • obstructive sleep apnea syndrome

Exclusion Criteria:

  • diabetes mellitus, chronic obstructive lung disease, coronary or valvular heart disease, congestive heart failure, renal failure, or endocrine dysfunction. Moreover, none of them were taking b-blockers, vasodilators, or inotropic agents at the time of enrollment in the study.
  Contacts and Locations
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Please refer to this study by its identifier: NCT00284037

Contact: Akiko Noda, PhD +81-52-719-1537

Nagoya University of Health Sciences Recruiting
Nagoya, Japan, 461-8673
Contact: Akiko Noda, PhD    +81-719-1537   
Principal Investigator: Akiko Noda, PhD         
Sponsors and Collaborators
Nagoya University
Study Chair: Mitsuhiro Yokota, MD.PhD Department of Cardiovascular Genome Science, Nagoya University School of Medicine, Nagoya, Aichi, Japan
  More Information Identifier: NCT00284037     History of Changes
Other Study ID Numbers: NU-06-A-0003
Study First Received: January 27, 2006
Last Updated: January 27, 2006

Keywords provided by Nagoya University:
obstructive sleep apnea,

Additional relevant MeSH terms:
Sleep Apnea Syndromes
Sleep Apnea, Obstructive
Respiration Disorders
Respiratory Tract Diseases
Sleep Disorders, Intrinsic
Sleep Wake Disorders
Nervous System Diseases processed this record on August 16, 2017