Effect of the Dietary Supplement SAMe on Blood Homocysteine Levels
|ClinicalTrials.gov Identifier: NCT00284011|
Recruitment Status : Completed
First Posted : January 31, 2006
Last Update Posted : January 6, 2012
|Condition or disease||Intervention/treatment|
|Heart Disease||Dietary Supplement: SAMe Other: Placebo|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||52 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Double (Participant, Investigator)|
|Official Title:||Effect of the Dietary Supplement S-Adenosyl-L-Methionine on Plasma Homocysteine Levels in Healthy Human Subjects|
|Study Start Date :||June 2005|
|Primary Completion Date :||April 2006|
|Study Completion Date :||May 2006|
Active Comparator: SAMe
Two 400 mg pills.
Dietary Supplement: SAMe
800 mg dose daily for 4 weeks.
Placebo Comparator: Placebo
Two placebo pills (identical in appearance to SAMe).
2 placebo pills daily for 4 weeks.
- Homocysteine levels pre- and post- one month of SAMe administration. [ Time Frame: 1 Month ]
- An interim (2 week) homocysteine level, high sensitivity C-reactive protein (hsCRP) level, lipid studies, and liver blood tests. [ Time Frame: 2 Weeks ]
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00284011
|United States, Minnesota|
|Rochester, Minnesota, United States, 55905|
|Principal Investigator:||Dietland Wahner-Roedler, M.D.||Mayo Clinic|