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Iscar for Second Line Treatment of Advanced Non-Small Cell Lung Cancer

This study has been completed.
Information provided by:
Kentuckiana Cancer Institute Identifier:
First received: January 26, 2006
Last updated: October 30, 2007
Last verified: October 2007
To determine if Iscar Quercus improves immune function and quality of life among patients with stage IV non-small cell lung cancer.

Condition Intervention
Non-Small Cell Lung Cancer
Drug: Iscar Quercus
Drug: Gemcitabine

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Randomized Pilot Study of Supplemental Iscar in Combination With Gemcitabine vs. Gemcitabine Alone as Second Line Treatment for Advanced Non-Small Cell Lung Cancer.

Resource links provided by NLM:

Further study details as provided by Kentuckiana Cancer Institute:

Primary Outcome Measures:
  • To determine if Iscar improves immune function and quality of life.

Estimated Enrollment: 20
Study Start Date: May 2004
Study Completion Date: April 2007
Detailed Description:
RAndomized pilot study of supplemental Iscar in combination with Gemcitabine vs. Gemcitabine alone as second line treatment for advanced non-small cell lung cancer.

Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • newly diagnosed IIIB and IV NSCLC who have failed one prior line of chemo
  • Karnofsky score 60% or greater
  • patients who will be treated with Gemcitabine
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00283478

United States, Kentucky
Kentuckiana Cancer Institute
Louisville, Kentucky, United States, 40202
Sponsors and Collaborators
Kentuckiana Cancer Institute
Study Director: Renato V. LaRocca, MD Kentuckiana Cancer Institute
  More Information Identifier: NCT00283478     History of Changes
Other Study ID Numbers: 1056757  Mistletoe 
Study First Received: January 26, 2006
Last Updated: October 30, 2007
Health Authority: United States: Food and Drug Administration

Keywords provided by Kentuckiana Cancer Institute:
Advanced stage
Lung cancer

Additional relevant MeSH terms:
Lung Neoplasms
Carcinoma, Non-Small-Cell Lung
Respiratory Tract Neoplasms
Thoracic Neoplasms
Neoplasms by Site
Lung Diseases
Respiratory Tract Diseases
Carcinoma, Bronchogenic
Bronchial Neoplasms
Antimetabolites, Antineoplastic
Molecular Mechanisms of Pharmacological Action
Antineoplastic Agents
Antiviral Agents
Anti-Infective Agents
Enzyme Inhibitors
Immunosuppressive Agents
Immunologic Factors
Physiological Effects of Drugs processed this record on October 21, 2016