ClinicalTrials.gov
ClinicalTrials.gov Menu

Prevention of Suicide in Primary Care Elderly: Collaborative Trial (PROSPECT)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT00279682
Recruitment Status : Completed
First Posted : January 19, 2006
Last Update Posted : January 19, 2006
Sponsor:
Collaborators:
University of Pennsylvania
University of Pittsburgh
National Institute of Mental Health (NIMH)
Forest Laboratories
The John A. Hartford Foundation
Information provided by:
Weill Medical College of Cornell University

Brief Summary:
The purpose of this study was to determine the effect of a primary care intervention on reducing suicidal ideation and depression in older patients.

Condition or disease Intervention/treatment Phase
Depression Suicide, Attempted Behavioral: treatment guidelines and depression care management Phase 4

Detailed Description:

Suicide rates are highest in late life; the majority of older adults who die by suicide have seen a primary care physician in preceding months. Depression is the strongest risk factor for late-life suicide and for suicide’s precursor, suicidal ideation.

The aim of the study was to determine the extent to which an intervention taht combined treatment guidelines with care management reduced rates of depression and suicide ideation in older primary care patients. The study randomized 20 primary care practices from New York City, Philadelphia, and Pittsburgh regions into intervention or usual car. The used a two-stage sampling design that resulted in a representative sample with an oversample of depressed patients (total n=1238 subjects including 598 with a depression diagnosis and 640 with no depression diagnosis). Patients were assessed at baseline, 4, 8, 12, 18 and 24 months.


Study Type : Interventional  (Clinical Trial)
Enrollment : 1200 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Prevention
Official Title: Prevention of Suicide in Primary Care Elderly: Collaborative Trial
Study Start Date : May 1999
Study Completion Date : August 2003

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Suicide




Primary Outcome Measures :
  1. Hamilton Depression Rating Scale
  2. Scale for Suicide Ideation

Secondary Outcome Measures :
  1. All cause and cause-specific mortality
  2. disability (Sf12; instrumental activities of daily living)


Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   60 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

upcoming appointment with primary care clinician

Exclusion Criteria:

  • inability to give consent
  • minimental status examination <18
  • ability to communicate in English

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00279682


Locations
United States, New York
Weill Medical College of Cornell University
White Plains, New York, United States, 10506
United States, Pennsylvania
Universilty of Pennsylvania
Philadelphia, Pennsylvania, United States, 19104
University of Pittsburgh
Pittsburgh, Pennsylvania, United States, 15213
Sponsors and Collaborators
Weill Medical College of Cornell University
University of Pennsylvania
University of Pittsburgh
National Institute of Mental Health (NIMH)
Forest Laboratories
The John A. Hartford Foundation
Investigators
Principal Investigator: George S Alexopoulos, MD Weill Medical College of Cornell University
Principal Investigator: Ira Katz, MD. Ph.D. University of Pennsylvania
Principal Investigator: Charles F Reynolds, MD University of Pittsburgh

Publications of Results:
Other Publications:
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
ClinicalTrials.gov Identifier: NCT00279682     History of Changes
Other Study ID Numbers: R01MH059366 ( U.S. NIH Grant/Contract )
R01MH059380 ( U.S. NIH Grant/Contract )
R01MH059381 ( U.S. NIH Grant/Contract )
First Posted: January 19, 2006    Key Record Dates
Last Update Posted: January 19, 2006
Last Verified: January 2006

Keywords provided by Weill Medical College of Cornell University:
depression
suicide
geriatric
elderly
primary care

Additional relevant MeSH terms:
Depression
Suicide
Suicide, Attempted
Behavioral Symptoms
Self-Injurious Behavior