This site became the new on June 19th. Learn more.
Show more Menu IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more... Menu IMPORTANT: Talk with a trusted healthcare professional before volunteering for a study. Read more... Menu
Give us feedback

Exercise and Shoe Orthoses in Treatment of Posterior Tibial Tendon Dysfunction

This study has been completed.
Information provided by (Responsible Party):
Kornelia Kulig, University of Southern California Identifier:
First received: January 17, 2006
Last updated: December 2, 2014
Last verified: December 2014
Posterior tibial tendon dysfunction (PTTD) is the most common cause of painful and debilitating acquired flatfoot deformity in adults. The dysfunction is often progressive and may result in attenuation of the PTT and eventually collapse of the plantar arch or even rupture of the tendon. Current therapeutic management of PTTD is multipronged and includes management with foot orthoses, stretching, and strengthening exercises. Evidence drawn from research related to the management of painful chronic Achilles tendinosis suggests that eccentric strengthening of the posterior tibialis may lead to superior results compared to concentric. The purpose of this research is to determine the effectiveness of treatment interventions used in the management of PTTD.

Condition Intervention Phase
Tendinopathy Procedure: Orthoses and Exercise Phase 1

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Phase 1 Study on Effectiveness of Exercise on Function, Quality of Life and Disability in Patients With Posterior Tibial Tendon Dysfunction

Resource links provided by NLM:

Further study details as provided by Kornelia Kulig, University of Southern California:

Primary Outcome Measures:
  • Foot Function Index; SF-36; walking distance in 5 minutes; time walking 50-ft; pain following the functional tests [ Time Frame: pre- post- 6-month post ]

Enrollment: 45
Study Start Date: June 2002
Study Completion Date: December 2014
Primary Completion Date: December 2014 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: type of exericse
type of exercise
Procedure: Orthoses and Exercise
orthrose and exercise - daily

Detailed Description:
All study participants receive a pair of custom made orthoses and perform daily calf-stretches. In addition to the orthoses two groups will perform tibialis posterior specific exercises; one as concentric and the second as eccentric activation. Intervention will last 12 weeks.

Ages Eligible for Study:   18 Years to 70 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Pain (> 3 months duration)
  • Pain localized to the medial ankle and foot
  • Swelling at the medial ankle
  • Able to perform a single controlled heel lowering

Exclusion Criteria:

  • Bilateral posterior tibial tendon dysfunction
  • Fixed foot deformities
  • Previous foot surgery
  • Presence of any other concurrent foot pathology besides posterior tibial tendon dysfunction
  • Ability to walk only with assistive device
  • Neurological disorders
  • Cognitive dysfunction
  • Uncontrolled cardiovascular disease
  • Evidence of cord compression
  • Uncontrolled hypertension
  • Infection
  • Severe respiratory disease
  • Pregnancy
  • Current or recent history of low back pain
  • Known rheumatic joint disease
  • Peripheral vascular disease with sensory loss of the foot.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00279630

United States, California
Department of Biokinesiology and Physical Therapy
Los Angeles, California, United States, 90089
Sponsors and Collaborators
University of Southern California
Principal Investigator: Kornelia Kulig, PhD, PT University of Southern California
  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Kornelia Kulig, Professor, University of Southern California Identifier: NCT00279630     History of Changes
Other Study ID Numbers: 022051
Study First Received: January 17, 2006
Last Updated: December 2, 2014

Keywords provided by Kornelia Kulig, University of Southern California:
Tibialis Posterior Tendinopathy

Additional relevant MeSH terms:
Posterior Tibial Tendon Dysfunction
Muscular Diseases
Musculoskeletal Diseases
Tendon Injuries
Wounds and Injuries
Foot Diseases processed this record on September 21, 2017