Activation and Recruitment of GIL During Hp Infection
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|ClinicalTrials.gov Identifier: NCT00275886|
Recruitment Status : Unknown
Verified December 2005 by National Taiwan University Hospital.
Recruitment status was: Recruiting
First Posted : January 12, 2006
Last Update Posted : January 12, 2006
|Condition or disease|
|Helicobacter Gastritis Dyspepsia|
Specific Aim #1: Characterization of the gastric infiltrating T cells from H. pylori gastritis patients A. Patients H. pylori infected gastritis and asymptomatic patients are selected from National Taiwan University hospital. The gastric biopsy specimen are taken from endoscopic biopsy in routine health check up or panendoscopic examination for the despeptic patients. HP negative gastritis patients will also be studied for negative control.
B. Immunohistochemical identification of T cells and expression of chemokine receptors.
Specific Aim #2 . Isolation and characterization of chemokines and chemokine receptors of the infiltrating lymphocytes in H. pylori-associated gastritis tissue
A. Isolation of gastric infiltrating lymphocyte B. Identification of the expression of chemokine receptor in gastric infiltrating lymphocytes by flow cytometry C. Detection of expression of chemokines in gastric tissues
|Study Type :||Observational|
|Estimated Enrollment :||30 participants|
|Observational Model:||Case Control|
|Official Title:||Activation and Recruitment of Gastric Infiltrating Lymphocytes During H. Pylori Infection|
|Study Start Date :||January 2006|
|Estimated Study Completion Date :||December 2008|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00275886
|Contact: Ping-Ning Hsu, MD, PhD||886-2-23123456 ext firstname.lastname@example.org|
|National Taiwan University Hospital||Recruiting|
|Contact: Ping-Ning Hsu, MD, PhD +886-223123456 ext 8635 email@example.com|
|Principal Investigator: Ping-Ning Hsu, MD, PhD|
|Principal Investigator:||Ping-Ning Hsu, MD, PhD||Department of Immunology|