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Acupuncture for Non-cyclical Breast Pain

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00275574
Recruitment Status : Completed
First Posted : January 12, 2006
Last Update Posted : January 1, 2016
Information provided by (Responsible Party):
Lori Thicke, Mayo Clinic

Brief Summary:
Breast pain or mastalgia is a common and troublesome symptom for many women. Whereas cyclical breast pain related to hormonal fluctuations can frequently be treated, non-cyclical breast pain can go untreated due to its various etiologies and non-specific presentation. Acupuncture is an ancient form of Chinese medicine that has been used for centuries to treat a vast array of illnesses and conditions. Research has shown that acupuncture has a link to a release of endorphins and other chemicals in the central nervous system. Thus, it is thought to help relieve pain. To date, there has been minimal research using acupuncture for breast pain. This pilot of 30 women will seek to determine whether four acupuncture treatments over a period of two weeks will significantly lower the level of pain experienced by these participants. Additionally, we will evaluate quality of life measures.

Condition or disease Intervention/treatment Phase
Breast Pain Procedure: acupuncture Not Applicable

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 30 participants
Allocation: N/A
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Acupuncture for the Treatment of Non-Cyclical Breast Pain
Study Start Date : April 2003
Actual Primary Completion Date : August 2009
Actual Study Completion Date : August 2009

Resource links provided by the National Library of Medicine

Arm Intervention/treatment
Experimental: acupuncture
four acupuncture treatments over a period of two weeks
Procedure: acupuncture

Primary Outcome Measures :
  1. Four acupuncture treatments over a period of two weeks can improve non-cyclical breast pain [ Time Frame: two weeks ]

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

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Ages Eligible for Study:   18 Years to 100 Years   (Adult, Older Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
  • Female
  • greater than 18 years
  • non-cyclical unilateral or bilateral breast pain occurring daily, Greater than or equal to 2 on the BPI (average pain question)
  • pain for more than 3 months
  • satisfactory (non-suspicious for malignancy) breast examination within one year of enrollment (need documentation from physician or advanced practice nurse)
  • satisfactory (non-suspicious for malignancy) mammogram and/or ultrasound within one year if Greater than 35 years(need written report to verify)
  • able to return for acupuncture two times a week for two weeks
  • speak and understand English
  • hormone replacement therapy discontinued > 3 months

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00275574

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United States, Minnesota
Mayo Clinic
Rochester, Minnesota, United States, 55905
Sponsors and Collaborators
Mayo Clinic
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Principal Investigator: Lori A. Thicke, R.N., M.S. Mayo Clinic
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Responsible Party: Lori Thicke, APRN CNS, Mayo Clinic Identifier: NCT00275574    
Other Study ID Numbers: 1975-02
First Posted: January 12, 2006    Key Record Dates
Last Update Posted: January 1, 2016
Last Verified: December 2015
Additional relevant MeSH terms:
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Neurologic Manifestations