Effect of Garlic on Inflammatory Mediators
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ClinicalTrials.gov Identifier: NCT00275405 |
Recruitment Status :
Suspended
(Results inconclusive)
First Posted : January 12, 2006
Last Update Posted : March 20, 2007
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Condition or disease | Intervention/treatment | Phase |
---|---|---|
Healthy | Drug: Garlic Oil Macerate | Phase 4 |
Study Type : | Interventional (Clinical Trial) |
Enrollment : | 34 participants |
Allocation: | Non-Randomized |
Intervention Model: | Parallel Assignment |
Masking: | None (Open Label) |
Primary Purpose: | Treatment |
Official Title: | Effect of Garlic Oil Macerate on Inflammatory Mediators in Healthy Normal Weight and Obese Subjects. |
Study Start Date : | April 2006 |
Estimated Study Completion Date : | March 2007 |

- 1. To examine the pharmacokinetics of the garlic oil macerate.
- 2. To examine the effect of garlic oil macerate on inflammatory mechanisms at the cellular and molecular level.

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Ages Eligible for Study: | 18 Years and older (Adult, Older Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
- 18 years of age and older
- Normal subjects with BMI <25, obese subjects with BMI >30
- Subjects who have consented to adhere to the diet, regular weekly visits, and blood draws.
Exclusion Criteria:
- Subjects on any antioxidant medication.
- Patient on non-steroidal anti-inflammatory drug.
- On any agent with antioxidant properties.
- History of drug or alcohol abuse.
- Any life threatening disease.
- On any agent with significant antioxidant properties.
- Taking garlic extracts in the diet regularly.

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00275405
United States, New York | |
Albany Medical Center | |
Albany, New York, United States, 12208 |
Principal Investigator: | Howard S Smith, MD | Albany Medical College | |
Principal Investigator: | Shaker A Mousa, PhD | Albany College of Pharmacy | |
Principal Investigator: | Ahmad Aljada, PhD | Albany College of Pharmacy |
ClinicalTrials.gov Identifier: | NCT00275405 |
Other Study ID Numbers: |
Ajoene |
First Posted: | January 12, 2006 Key Record Dates |
Last Update Posted: | March 20, 2007 |
Last Verified: | March 2007 |
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