Nonalcoholic Fatty Liver Disease in Taiwanese Children
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00274183|
Recruitment Status : Recruiting
First Posted : January 10, 2006
Last Update Posted : March 30, 2017
|Condition or disease|
[Study Subjects] Obesity was defined as the BMI value > 95 percentile by different age- and gender groups according to the standards of the Department of Health in Taiwan.
[Data Collection] The following data were obtained for each subject: age, gender, BMI, waist and hip circumference. BMI was calculated as body weight (kg)/ height (m2).
In fasting venous blood samples, we measured total serum bilirubin, alanine aminotransferase, aspartate aminotransferase, γ-glutamyltransferase, fasting glucose, triglyceride, total cholesterol,high-density lipoprotein cholesterol, insulin, glucose, and adiponectin.
[Liver Ultrasonography] All participants underwent an ultrasonographic study of the liver performed by one operator.
NAFLD was defined as the presence of an ultrasonographic pattern consistent with the following criteria: liver-kidney echo discrepancy, attenuated echo penetration and visibility of diaphragm, and obscure hepatic vessel structures.
|Study Type :||Observational|
|Estimated Enrollment :||800 participants|
|Official Title:||Prevalence, Clinicopathological Characteristics, Biomarkers and Genetics of Nonalcoholic Steatohepatitis in Taiwanese Children|
|Study Start Date :||January 2006|
|Estimated Primary Completion Date :||December 2017|
|Estimated Study Completion Date :||December 2019|
- non-alcoholic fatty liver disease confirmed by liver ultrasonography [ Time Frame: one year ]
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00274183
|Contact: Yu-Cheng Lin, M.D.||886-2-89667000 ext firstname.lastname@example.org|
|Far Eastern Memorial Hospital||Recruiting|
|Taipei, Taiwan, 220|
|Contact: Yu-Cheng Lin, MD 0931122487 email@example.com|
|Principal Investigator:||Yu-Cheng Lin, M.D.||Far Eastern Memorial Hospital|