Nonalcoholic Fatty Liver Disease in Taiwanese Children
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|ClinicalTrials.gov Identifier: NCT00274183|
Recruitment Status : Recruiting
First Posted : January 10, 2006
Last Update Posted : March 30, 2017
|Condition or disease|
[Study Subjects] Obesity was defined as the BMI value > 95 percentile by different age- and gender groups according to the standards of the Department of Health in Taiwan.
[Data Collection] The following data were obtained for each subject: age, gender, BMI, waist and hip circumference. BMI was calculated as body weight (kg)/ height (m2).
In fasting venous blood samples, we measured total serum bilirubin, alanine aminotransferase, aspartate aminotransferase, γ-glutamyltransferase, fasting glucose, triglyceride, total cholesterol,high-density lipoprotein cholesterol, insulin, glucose, and adiponectin.
[Liver Ultrasonography] All participants underwent an ultrasonographic study of the liver performed by one operator.
NAFLD was defined as the presence of an ultrasonographic pattern consistent with the following criteria: liver-kidney echo discrepancy, attenuated echo penetration and visibility of diaphragm, and obscure hepatic vessel structures.
|Study Type :||Observational|
|Estimated Enrollment :||800 participants|
|Official Title:||Prevalence, Clinicopathological Characteristics, Biomarkers and Genetics of Nonalcoholic Steatohepatitis in Taiwanese Children|
|Study Start Date :||January 2006|
|Estimated Primary Completion Date :||December 2017|
|Estimated Study Completion Date :||December 2019|
- non-alcoholic fatty liver disease confirmed by liver ultrasonography [ Time Frame: one year ]
Biospecimen Retention: Samples With DNA
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00274183
|Contact: Yu-Cheng Lin, M.D.||886-2-89667000 ext firstname.lastname@example.org|
|Far Eastern Memorial Hospital||Recruiting|
|Taipei, Taiwan, 220|
|Contact: Yu-Cheng Lin, MD 0931122487 email@example.com|
|Principal Investigator:||Yu-Cheng Lin, M.D.||Far Eastern Memorial Hospital|