Neoadjuvant Chemotherapy Plus/Minus Surgery in Non-Small-Cell Lung Cancer (NSCLC) Stage IIIA/N2
The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified May 2008 by Rigshospitalet, Denmark.
Recruitment status was: Recruiting
Information provided by:
First received: January 5, 2006
Last updated: May 21, 2008
Last verified: May 2008
Hypothesis is that surgery is of benefit in locally advanced NSCLC with N2 disease.
Patients are randomised to surgery or not.
Non-Small Cell Lung Cancer
Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
||Scandinavian Neoadjuvant Phase III Study of Induction Chemotherapy Followed by Irradiation Alone or Surgery Plus Irradiation in NSCLC Stage IIIA/N2 (T1N2, T2N2, T3/N2).
Primary Outcome Measures:
Secondary Outcome Measures:
| Estimated Enrollment:
| Study Start Date:
| Estimated Study Completion Date:
Patients are after staging randomised to neoadj. chemotherapy followed by surgery followed by irradiation or to chemotherapy followed by irradiation.
Endpoint is survival.
|Ages Eligible for Study:
||18 Years to 75 Years (Adult, Senior)
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
- Histologically verified NSCLC
- Stage IIIA/N2
- age 18-75
- Lung function test allowing surgery
- Mediastinoscopy performed
- Prior chemotherapy
- Prior irradiation
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study.
To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below.
For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00273494
|Dept. Oncology, Rigshospitalet
|Copenhagen, Denmark, 2100 |
||Jens B. Sorensen, MD
History of Changes
|Other Study ID Numbers:
Surgery in NSCLC stage IIIA/N2
|Study First Received:
||January 5, 2006
||May 21, 2008
||Denmark: National Board of Health
Keywords provided by Rigshospitalet, Denmark:
Non-small cell lung cancer
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on December 06, 2016
Carcinoma, Non-Small-Cell Lung
Respiratory Tract Neoplasms
Neoplasms by Site
Respiratory Tract Diseases