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An Intervention to Reduce Inappropriate Prescriptions of Antibiotics for Respiratory Infections in General Practice

This study has been completed.
Information provided by:
University of Oslo Identifier:
First received: January 3, 2006
Last updated: April 26, 2010
Last verified: December 2005
This study will explore the possible effect of a tailored educational intervention towards general practitioners, in order to improve antibiotic prescriptions for respiratory infections.

Condition Intervention Phase
Respiratory Tract Infections
Anti-Bacterial Agents
Behavioral: Educational intervention
Behavioral: Educational intervention program
Phase 1
Phase 2

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Health Services Research
Official Title: Can Antibiotic Prescriptions in Respiratory Tract Infections be Improved? A Cluster Randomized Educational Intervention in General Practice

Resource links provided by NLM:

Further study details as provided by University of Oslo:

Primary Outcome Measures:
  • Change in antibiotic prescription patterns for respiratory infections [ Time Frame: 1 year ]
    From the 1.336.717 office consultations, main outcomes data (baseline proportion of inappropriate antibiotic prescriptions for RTIs and change in prescription patterns compared to baseline) was measured 1 year after the initiation of the tailored pedagogic intervention.

Enrollment: 118621
Study Start Date: January 2006
Study Completion Date: March 2007
Primary Completion Date: March 2007 (Final data collection date for primary outcome measure)
Intervention Details:
    Behavioral: Educational intervention
    Educational outreach visits to the CME-groups, work-shops, audit and feedback
    Behavioral: Educational intervention program
    The 433 recruited GPs had a total of 1336 717 office consultations of which 171 679 (12.8%) were RTIs encounters for 118 621 different patients. The GPs participated in peer continuing medical education (CME) groups in southern Norway. A multifaceted intervention was tailored, where key components were educational outreach visits to the CME-groups, work-shops, audit and feedback. Prescription Peer Academic Detailers conducted the educational outreach visits. During these visits, evidence-based recommendations of antibiotic prescriptions for RTIs were presented and software handed out for installation in participants PCs, enabling collection of prescription data. These data was linked to corresponding data from the Norwegian Prescription Database (NorPD). Main outcomes are baseline proportion of inappropriate antibiotic prescriptions for RTIs and change in prescription patterns compared to baseline one year after the initiation of the tailored pedagogic intervention.

Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • General practitioner
  • Specialist in general practice
  Contacts and Locations
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Please refer to this study by its identifier: NCT00272155

University of Oslo
Oslo, Norway
Sponsors and Collaborators
University of Oslo
Principal Investigator: Svein Gjelstad, MD University of Oslo
  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Jorund Straand, Professor Md PhD, University of Oslo Identifier: NCT00272155     History of Changes
Other Study ID Numbers: 850657
Study First Received: January 3, 2006
Last Updated: April 26, 2010

Additional relevant MeSH terms:
Communicable Diseases
Respiratory Tract Infections
Respiratory Tract Diseases
Anti-Bacterial Agents
Antibiotics, Antitubercular
Anti-Infective Agents
Antitubercular Agents processed this record on April 28, 2017