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Multifunctional Substrate for Early Detection of Oxidative Stress Susceptibility and Application to Parkinson's Disease

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ClinicalTrials.gov Identifier: NCT00271141
Recruitment Status : Unknown
Verified December 2005 by Hillel Yaffe Medical Center.
Recruitment status was:  Recruiting
First Posted : December 30, 2005
Last Update Posted : December 30, 2005
Sponsor:
Collaborator:
Technion, Israel Institute of Technology
Information provided by:
Hillel Yaffe Medical Center

Brief Summary:
The proposed work is based on the detection of a novel molecule for sensitivity to oxidative stress in humans in venous blood

Condition or disease
Parkinson's Disease Oxidative Stress

Detailed Description:
Since alterations in mitochondrial functions in platelets and lymphocytes have been detected in Parkinson's disease we plan to monitor the metabolism a a new molecule (LTG) in the blood samples of Parkinson's disease patients and compare them to controls. We shall use 10 cc of venous blood and analyze serum, white blood cells and platelets. We shall not extract nor use DNA.The main purpose is to develop a marker for Parkinson's disease in venous blood.

Study Type : Observational
Enrollment : 500 participants
Primary Purpose: Screening
Time Perspective: Cross-Sectional
Time Perspective: Retrospective
Official Title: Multifunctional Substrate for Early Detection of Oxidative Stress Susceptibility and Application to Parkinson's Disease
Study Start Date : May 2005
Study Completion Date : December 2015

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

Parkinson's disease Healthy control -

Exclusion Criteria:

None -


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To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00271141


Contacts
Contact: Rivka Inzelberg, MD +972-4-6304607 inzelberg@hy.health.gov.il

Locations
Israel
Hillel Yaffe Medical Center Recruiting
Hadera, Israel
Principal Investigator: Rivka Inzelberg, MD         
Sponsors and Collaborators
Hillel Yaffe Medical Center
Technion, Israel Institute of Technology
Investigators
Principal Investigator: Rivka Inzelberg, MD Hillel Yaffe Medical Center

ClinicalTrials.gov Identifier: NCT00271141     History of Changes
Other Study ID Numbers: hy11/2005
First Posted: December 30, 2005    Key Record Dates
Last Update Posted: December 30, 2005
Last Verified: December 2005

Keywords provided by Hillel Yaffe Medical Center:
Parkinson's disease
Oxidative stress
Marker

Additional relevant MeSH terms:
Parkinson Disease
Disease Susceptibility
Parkinsonian Disorders
Basal Ganglia Diseases
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Movement Disorders
Neurodegenerative Diseases
Disease Attributes
Pathologic Processes