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Data and Sample Collection Study to Elucidate the Mechanisms of Eosinophilic Disorders

This study is currently recruiting participants. (see Contacts and Locations)
Verified September 2014 by Children's Hospital Medical Center, Cincinnati
Information provided by (Responsible Party):
Children's Hospital Medical Center, Cincinnati Identifier:
First received: December 15, 2005
Last updated: November 10, 2015
Last verified: September 2014
The purpose of this study is to elucidate the mechanisms underlying eosinophil growth, survival, migration, and function and to investigate and further characterize the pathophysiology of, clinical manifestations of, and spectrum of disease severity of eosinophilic inflammation in humans.

Eosinophilic Gastrointestinal Disease Eosinophilic Inflammatory Disease
Food Allergy

Study Type: Observational
Study Design: Time Perspective: Prospective
Official Title: Eosinophils and Inflammation, an Expanded Study

Resource links provided by NLM:

Further study details as provided by Children's Hospital Medical Center, Cincinnati:

Estimated Enrollment: 5000
Study Start Date: May 2005
Estimated Study Completion Date: January 2050
Estimated Primary Completion Date: January 2050 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Patients with eosinophilic disorders and patients without eosinophilic disorders to serve as normal controls

Inclusion Criteria:

  • Signed informed consent obtained from the patient or parent/guardian. Assent will be obtained from all minors 11 years of age and older.
  • Carrying a diagnosis of eosinophilic gastrointestinal disease, eosinophilic inflammatory disease, or food allergy OR family member, or normal control
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00267501

Contact: Jonathan Kuhl, BS 513-803-3078

United States, Ohio
Cincinnati Children's Hospital Medical Center Recruiting
Cincinnati, Ohio, United States, 45229-3039
Principal Investigator: Marc E. Rothenberg, M.D., Ph.D.         
Sponsors and Collaborators
Children's Hospital Medical Center, Cincinnati
Principal Investigator: Marc E. Rothenberg, M.D., Ph.D. Children's Hospital Medical Center, Cincinnati
  More Information

Responsible Party: Children's Hospital Medical Center, Cincinnati Identifier: NCT00267501     History of Changes
Other Study ID Numbers: 04-12-8
R01 DK075401
Study First Received: December 15, 2005
Last Updated: November 10, 2015

Keywords provided by Children's Hospital Medical Center, Cincinnati:
Eosinophilic Disorders

Additional relevant MeSH terms:
Food Hypersensitivity
Gastrointestinal Diseases
Digestive System Diseases
Hypersensitivity, Immediate
Immune System Diseases
Leukocyte Disorders
Hematologic Diseases processed this record on May 25, 2017