A Clinical Trial Comparing Torcetrapib/Atorvastatin To Simvastatin In Subjects With High Cholesterol.
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|ClinicalTrials.gov Identifier: NCT00267254|
Recruitment Status : Completed
First Posted : December 20, 2005
Last Update Posted : November 21, 2007
The Torcetrapib project was terminated on December 2, 2006 due to safety findings.
Cholesterol levels will be measured over six weeks in subjects being treated with two different kinds of cholesterol medications to see how the different treatments compare to one another.
|Condition or disease||Intervention/treatment||Phase|
|Hyperlipidemia Dyslipidemia Hypercholesterolemia||Drug: torcetrapib/atorvastatin Drug: simvastatin||Phase 3|
|Study Type :||Interventional (Clinical Trial)|
|Enrollment :||640 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Official Title:||A Phase 3, Open-Label, Multisite, Randomized, Parallel Group Study of the Efficacy and Safety of Fixed Combination Torcetrapib/Atorvastatin Administered Once Daily (QD) Compared to Simvastatin for 6 Weeks in Subjects With Hypercholesterolemia (A5091030)|
|Study Start Date :||January 2006|
|Actual Study Completion Date :||August 2006|
- Percent change in LDL-C and HDL-C from baseline, after six weeks of treatment.
- Changes in other lipid parameters and other biomarkers.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00267254
|Study Director:||Pfizer CT.gov Call Center||Pfizer|