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The Molecular Mechanism and the Role of NRAMP 1gene on Tuberculosis in Taiwan Aboriginal Tribes Population

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ClinicalTrials.gov Identifier: NCT00266383
Recruitment Status : Completed
First Posted : December 16, 2005
Last Update Posted : December 19, 2005
Sponsor:
Information provided by:

Study Description
Brief Summary:
The human homologue of mice natural-resistance-associated macrophage protein 1 (Nramp 1) gene, NRAMP 1, has been reported to play a role in the susceptibility to tuberculosis in humans. The aboriginal population in Taiwan has a 5-fold higher prevalence of tuberculosis than the Han Chinese. Whether genetic factors such as NRAMP 1 polymorphisms play a role in the prevalence of tuberculosis in Taiwanese aboriginals should be clarified.

Condition or disease
Tuberculosis

Study Design

Study Type : Observational
Estimated Enrollment : 250 participants
Observational Model: Case Control
Time Perspective: Longitudinal
Time Perspective: Retrospective/Prospective
Official Title: The Molecular Mechanism and the Role of NRAMP 1gene on Tuberculosis in Taiwan Aboriginal Tribes Population
Study Start Date : January 2005
Estimated Study Completion Date : December 2005

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Groups and Cohorts


Outcome Measures

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • The NRAMP 1 polymorphism of tuberculous patients in Taiwan.

Exclusion Criteria:

Contacts and Locations

Information from the National Library of Medicine

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Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00266383


Locations
Taiwan
National Health Research Institutes
Miaoli county, Taiwan
Sponsors and Collaborators
National Health Research Institutes, Taiwan
Investigators
Principal Investigator: Ih-Jen Su, M.D., Ph.D. Division of Clinical Research, National Health Research Institutes
More Information

ClinicalTrials.gov Identifier: NCT00266383     History of Changes
Other Study ID Numbers: DOH94-DC-1009
First Posted: December 16, 2005    Key Record Dates
Last Update Posted: December 19, 2005
Last Verified: December 2005

Additional relevant MeSH terms:
Tuberculosis
Mycobacterium Infections
Actinomycetales Infections
Gram-Positive Bacterial Infections
Bacterial Infections