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The Molecular Mechanism and the Role of NRAMP 1gene on Tuberculosis in Taiwan Aboriginal Tribes Population

This study has been completed.
Information provided by:
National Health Research Institutes, Taiwan Identifier:
First received: December 15, 2005
Last updated: December 16, 2005
Last verified: December 2005
The human homologue of mice natural-resistance-associated macrophage protein 1 (Nramp 1) gene, NRAMP 1, has been reported to play a role in the susceptibility to tuberculosis in humans. The aboriginal population in Taiwan has a 5-fold higher prevalence of tuberculosis than the Han Chinese. Whether genetic factors such as NRAMP 1 polymorphisms play a role in the prevalence of tuberculosis in Taiwanese aboriginals should be clarified.


Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Longitudinal
Time Perspective: Retrospective/Prospective
Official Title: The Molecular Mechanism and the Role of NRAMP 1gene on Tuberculosis in Taiwan Aboriginal Tribes Population

Resource links provided by NLM:

Further study details as provided by National Health Research Institutes, Taiwan:

Estimated Enrollment: 250
Study Start Date: January 2005
Estimated Study Completion Date: December 2005

Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • The NRAMP 1 polymorphism of tuberculous patients in Taiwan.

Exclusion Criteria:

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Please refer to this study by its identifier: NCT00266383

National Health Research Institutes
Miaoli county, Taiwan
Sponsors and Collaborators
National Health Research Institutes, Taiwan
Principal Investigator: Ih-Jen Su, M.D., Ph.D. Division of Clinical Research, National Health Research Institutes
  More Information Identifier: NCT00266383     History of Changes
Other Study ID Numbers: DOH94-DC-1009
Study First Received: December 15, 2005
Last Updated: December 16, 2005

Additional relevant MeSH terms:
Mycobacterium Infections
Actinomycetales Infections
Gram-Positive Bacterial Infections
Bacterial Infections processed this record on May 25, 2017