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The Molecular Mechanism and the Role of NRAMP 1gene on Tuberculosis in Taiwan Aboriginal Tribes Population

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00266383
First Posted: December 16, 2005
Last Update Posted: December 19, 2005
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
National Health Research Institutes, Taiwan
  Purpose
The human homologue of mice natural-resistance-associated macrophage protein 1 (Nramp 1) gene, NRAMP 1, has been reported to play a role in the susceptibility to tuberculosis in humans. The aboriginal population in Taiwan has a 5-fold higher prevalence of tuberculosis than the Han Chinese. Whether genetic factors such as NRAMP 1 polymorphisms play a role in the prevalence of tuberculosis in Taiwanese aboriginals should be clarified.

Condition
Tuberculosis

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Longitudinal
Time Perspective: Retrospective/Prospective
Official Title: The Molecular Mechanism and the Role of NRAMP 1gene on Tuberculosis in Taiwan Aboriginal Tribes Population

Resource links provided by NLM:


Further study details as provided by National Health Research Institutes, Taiwan:

Estimated Enrollment: 250
Study Start Date: January 2005
Estimated Study Completion Date: December 2005
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • The NRAMP 1 polymorphism of tuberculous patients in Taiwan.

Exclusion Criteria:

  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00266383


Locations
Taiwan
National Health Research Institutes
Miaoli county, Taiwan
Sponsors and Collaborators
National Health Research Institutes, Taiwan
Investigators
Principal Investigator: Ih-Jen Su, M.D., Ph.D. Division of Clinical Research, National Health Research Institutes
  More Information

ClinicalTrials.gov Identifier: NCT00266383     History of Changes
Other Study ID Numbers: DOH94-DC-1009
First Submitted: December 15, 2005
First Posted: December 16, 2005
Last Update Posted: December 19, 2005
Last Verified: December 2005

Additional relevant MeSH terms:
Tuberculosis
Mycobacterium Infections
Actinomycetales Infections
Gram-Positive Bacterial Infections
Bacterial Infections