Pilot Study of Aspirin Versus Warfarin for Cervicocephalic Arterial Dissection

This study has been withdrawn prior to enrollment.
Information provided by:
University of California, San Diego
ClinicalTrials.gov Identifier:
First received: December 12, 2005
Last updated: December 5, 2014
Last verified: March 2007
Pilot Study of Aspirin Versus Warfarin for Cervicocephalic Arterial Dissection.

Condition Intervention Phase
Ischemic Stroke
Drug: aspirin
Drug: warfarin
Phase 1

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Pilot Study of Aspirin Versus Warfarin for Cervicocephalic Arterial Dissection

Resource links provided by NLM:

Further study details as provided by University of California, San Diego:

Primary Outcome Measures:
  • Incidence of stroke by one year. [ Time Frame: 1 year ]

Secondary Outcome Measures:
  • Recurrent dissection by one year. [ Time Frame: 1 year ]
  • Incidence of TIA by one year. [ Time Frame: 1 year ]
  • Incidence of major and minor bleeding episodes by one year. [ Time Frame: 1 year ]

Enrollment: 0
Study Start Date: December 2005
Estimated Study Completion Date: March 2007
Arms Assigned Interventions
Experimental: aspirin Drug: aspirin
Experimental: warfarin Drug: warfarin

Detailed Description:
20 patients with cervicocephalic arterial dissection will be randomized to open-label aspirin or warfarin, rate of stroke and adverse events will be endpoints.

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Clinical and imaging diagnosis of cervicocephalic arterial dissection within 3 months.

Exclusion Criteria:

  • Any contraindication to aspirin or warfarin.
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00265408

United States, California
UCSD Medical Center
San Diego, California, United States, 92103
Sponsors and Collaborators
University of California, San Diego
Principal Investigator: Matt B Jensen, MD UCSD Stroke Center
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT00265408     History of Changes
Other Study ID Numbers: UCSD IRB #051253
Study First Received: December 12, 2005
Last Updated: December 5, 2014
Health Authority: United States: Institutional Review Board

Keywords provided by University of California, San Diego:
Cervicocephalic Arterial Dissection

Additional relevant MeSH terms:
Aneurysm, Dissecting
Cardiovascular Diseases
Vascular Diseases
Analgesics, Non-Narcotic
Anti-Inflammatory Agents
Anti-Inflammatory Agents, Non-Steroidal
Antirheumatic Agents
Cardiovascular Agents
Central Nervous System Agents
Cyclooxygenase Inhibitors
Enzyme Inhibitors
Fibrin Modulating Agents
Fibrinolytic Agents
Hematologic Agents
Molecular Mechanisms of Pharmacological Action
Peripheral Nervous System Agents
Pharmacologic Actions
Physiological Effects of Drugs
Platelet Aggregation Inhibitors
Sensory System Agents
Therapeutic Uses

ClinicalTrials.gov processed this record on November 27, 2015