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Pilot Study of Aspirin Versus Warfarin for Cervicocephalic Arterial Dissection

This study has been withdrawn prior to enrollment.
Information provided by:
University of California, San Diego Identifier:
First received: December 12, 2005
Last updated: December 5, 2014
Last verified: March 2007
Pilot Study of Aspirin Versus Warfarin for Cervicocephalic Arterial Dissection.

Condition Intervention Phase
Ischemic Stroke
Drug: aspirin
Drug: warfarin
Phase 1

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Pilot Study of Aspirin Versus Warfarin for Cervicocephalic Arterial Dissection

Resource links provided by NLM:

Further study details as provided by University of California, San Diego:

Primary Outcome Measures:
  • Incidence of stroke by one year. [ Time Frame: 1 year ]

Secondary Outcome Measures:
  • Recurrent dissection by one year. [ Time Frame: 1 year ]
  • Incidence of TIA by one year. [ Time Frame: 1 year ]
  • Incidence of major and minor bleeding episodes by one year. [ Time Frame: 1 year ]

Enrollment: 0
Study Start Date: December 2005
Estimated Study Completion Date: March 2007
Arms Assigned Interventions
Experimental: aspirin Drug: aspirin
Experimental: warfarin Drug: warfarin

Detailed Description:
20 patients with cervicocephalic arterial dissection will be randomized to open-label aspirin or warfarin, rate of stroke and adverse events will be endpoints.

Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Clinical and imaging diagnosis of cervicocephalic arterial dissection within 3 months.

Exclusion Criteria:

  • Any contraindication to aspirin or warfarin.
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Please refer to this study by its identifier: NCT00265408

United States, California
UCSD Medical Center
San Diego, California, United States, 92103
Sponsors and Collaborators
University of California, San Diego
Principal Investigator: Matt B Jensen, MD UCSD Stroke Center
  More Information Identifier: NCT00265408     History of Changes
Other Study ID Numbers: UCSD IRB #051253
Study First Received: December 12, 2005
Last Updated: December 5, 2014

Keywords provided by University of California, San Diego:
Cervicocephalic Arterial Dissection

Additional relevant MeSH terms:
Aneurysm, Dissecting
Vascular Diseases
Cardiovascular Diseases
Anti-Inflammatory Agents, Non-Steroidal
Analgesics, Non-Narcotic
Sensory System Agents
Peripheral Nervous System Agents
Physiological Effects of Drugs
Anti-Inflammatory Agents
Antirheumatic Agents
Fibrinolytic Agents
Fibrin Modulating Agents
Molecular Mechanisms of Pharmacological Action
Platelet Aggregation Inhibitors
Cyclooxygenase Inhibitors
Enzyme Inhibitors
Anticoagulants processed this record on May 23, 2017