The Prevalence and Clinical Manifestations of Human Metapneumovirus Among Children With Bronchiolitis.

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00265187
Recruitment Status : Completed
First Posted : December 14, 2005
Last Update Posted : January 3, 2013
Information provided by:
HaEmek Medical Center, Israel

Brief Summary:
Sputum specimens will be obtained from children < 2 years of age and processed by different mode for the HMPV, RSV, Pertussis, Influenza A, B, Parainfluenza 1,2,3, Adenovirus. Clinical and epidemiological data will also be obtained.

Condition or disease
Respiratory Tract Infection Children

Detailed Description:
The purpose of the study is to asses the various pathogens of bronchiolitis in children and its' clinical manifestations. Prospective study in 3 Medical centers in Northern Israel. Included will be about 200 infants and children < 2 years hospitalized with bronchiolitis. From each child sputum specimen will be obtained and processed for HUMP - PCR, Pertussis - PCR, RSV - ELISA, DFA, PCR, Influenza A, B, Parainfluenza 1,2,3 - DFA, PCR, Adenovirus - DFA. Epidemiological data will be obtained for every child by structured questioner. Clinical data will be daily obtained by scoring system.

Study Type : Observational
Actual Enrollment : 200 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: The Prevalence and Clinical Manifestations of Human Metapneumovirus Among Children With Bronchiolitis in Northern Israel.
Study Start Date : December 2005
Actual Primary Completion Date : March 2006
Actual Study Completion Date : March 2006

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Ages Eligible for Study:   up to 2 Years   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Children 0-24 months hospitalized with acute bronchiolitis

Inclusion Criteria:Age 0-24 months, hospitalized children, -

Exclusion Criteria:Previous hospitalization, previous RSV immunization, immunocompromised patient, previous inclusion in this study, inclusion in another study.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00265187

Pediatric department A, HaEmek Medical Center
Afula, Israel
Maier Hospital
Haifa, Israel
Pediatric Depart ment , Bnai Zion Hospital
Haifa, Israel
Sponsors and Collaborators
HaEmek Medical Center, Israel
Principal Investigator: Dan Miron, MD HaEmek Medicak Center, Afula, Israel

Responsible Party: Dan Miron, MD, HaEmek Medical Center, Afula, Israel Identifier: NCT00265187     History of Changes
Other Study ID Numbers: 3350105
First Posted: December 14, 2005    Key Record Dates
Last Update Posted: January 3, 2013
Last Verified: August 2006

Keywords provided by HaEmek Medical Center, Israel:
child, bronchiolitis,

Additional relevant MeSH terms:
Respiratory Tract Infections
Bronchial Diseases
Respiratory Tract Diseases
Lung Diseases, Obstructive
Lung Diseases