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Cortical Reorganisation in Patients With Primary Headache Disorders

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified August 2005 by Danish Headache Center.
Recruitment status was:  Active, not recruiting
Information provided by:
Danish Headache Center Identifier:
First received: December 9, 2005
Last updated: NA
Last verified: August 2005
History: No changes posted
Primary headache disorders are now accepted as physiological diseases, and advanced imaging-techniques have demonstrated a migraine generator in the brain stem and increased stimulus sensitivity in these patients. The underlying neuronal dysfunctions remain to to clarified and the existing neurophysiological methods have not yet been useful. More sensitive and reliable methods are therefore highly needed. The aims of the study are therefore to develop a sensitive and reliable method to demonstrate a cortical reorganisation and expansion of pain sensitive cortical areas in patients with migraine or tension-type headache.

Condition Intervention
Migraine Without Aura Chronic Tension-Type Headache Device: EEC-techniques

Study Type: Observational
Study Design: Observational Model: Case Control
Primary Purpose: Screening
Time Perspective: Cross-Sectional
Time Perspective: Prospective
Official Title: Cortical Reorganisation in Patients With Primary Headache Disorders

Resource links provided by NLM:

Further study details as provided by Danish Headache Center:


Ages Eligible for Study:   18 Years to 65 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Clinical diagnosis og migraine without aura or chronic tension-type headache

Exclusion Criteria:

  • serious somatic or psychiatric diseases including depression
  • overuse of analgesics
  • regular intake of opiates or benzodiazepines
  • intake of prophylactic headache medication
  • pregnancy
  Contacts and Locations
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Please refer to this study by its identifier: NCT00263991

Danish Headache Center; Department of Neurology, Glostrup Hospital, University of Copenhagen
Glostrup, Copenhagen, Denmark, 2600
Sponsors and Collaborators
Danish Headache Center
Principal Investigator: Lars Bendtsen, MD, Ph.d Danish Headache Center, Department of Neurology, Glostrup Hospital, University of Copenhagen, Denmark
  More Information Identifier: NCT00263991     History of Changes
Other Study ID Numbers: KA 05085
Study First Received: December 9, 2005
Last Updated: December 9, 2005

Additional relevant MeSH terms:
Headache Disorders
Headache Disorders, Primary
Tension-Type Headache
Migraine without Aura
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms
Brain Diseases
Central Nervous System Diseases
Migraine Disorders processed this record on September 21, 2017