Pathophysiological Mechanisms of Hepatopulmonary Influence in the Fontan Circulation
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|ClinicalTrials.gov Identifier: NCT00263406|
Recruitment Status : Completed
First Posted : December 8, 2005
Last Update Posted : December 28, 2007
|Condition or disease||Intervention/treatment||Phase|
|Children With a Univentricular Heart Undergoing Surgery for Creation of a Fontan Circulation||Drug: Administration of an ACE-inhibitor or not||Phase 2|
Children that are undergoing elective surgery for the creation of a Fontan circulation will be randomised to postoperative administration of an ACE-inhibitor or not.
Determination of aldosteron, renine and ADH in serum preoperatively and 1h, 12h and 5 days postoperatively.
|Study Type :||Interventional (Clinical Trial)|
|Enrollment :||40 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Pathophysiological Mechanisms of Hepatopulmonary Influence in the Fontan Circulation|
|Study Start Date :||December 2002|
|Actual Study Completion Date :||March 2007|
- Duration of the pleural drainage in the first two postoperative weeks
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00263406
|University Hospital Ghent|
|Ghent, Belgium, 9000|
|Principal Investigator:||Guy Van Nooten, MD, PhD||University Hospital, Ghent|