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Investigation on the Role of Corticosteroids and Beta-Agonists on Cytokine Production in COPD Patients

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ClinicalTrials.gov Identifier: NCT00263380
Recruitment Status : Unknown
Verified July 2005 by St. Antonius Hospital.
Recruitment status was:  Recruiting
First Posted : December 8, 2005
Last Update Posted : September 11, 2006
Sponsor:
Information provided by:
St. Antonius Hospital

Brief Summary:
Research on the synergistic effect of corticosteroids and beta-agonists on the cytokine production in COPD patients. Blood will be obtained from healthy volunteers and COPD patients and blood monocytes will be stimulated to produce cytokines with or without the prementioned drugs.

Condition or disease
COPD

Study Type : Observational
Enrollment : 90 participants
Observational Model: Case Control
Primary Purpose: Screening
Time Perspective: Longitudinal
Time Perspective: Prospective
Official Title: Experimental Study on the Role of Corticosteroids and Beta-Agonists on Cytokine Production in COPD Patients
Study Start Date : October 2005

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Steroids
U.S. FDA Resources





Information from the National Library of Medicine

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Ages Eligible for Study:   40 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • clinical COPD
  • smoking
  • age > 40 years

Exclusion Criteria:

  • age < 40 years
  • use of antibiotics, corticosteroids or beta-agonists

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00263380


Locations
Netherlands
St Antonius Hospital Recruiting
Nieuwegein, Utrecht, Netherlands, 3435 CM
Contact: Robert Ten Broeke, Dr    + 31 30 609111    r.broeke@kf-antoniusmesosgroep.nl   
Principal Investigator: Robert Ten Broeke, Dr         
St Antonius Hospital Recruiting
Nieuwegein, Utrecht, Netherlands, 3435 CM
Contact: Robert Ten Broeke, Dr    + 31 30 6091111    r.broeke@kf-antoniusmesosgroep.nl   
Sponsors and Collaborators
St. Antonius Hospital
Investigators
Principal Investigator: Robert Ten Broeke, Dr St. Antonius Hospital

ClinicalTrials.gov Identifier: NCT00263380     History of Changes
Other Study ID Numbers: COPD IL8
First Posted: December 8, 2005    Key Record Dates
Last Update Posted: September 11, 2006
Last Verified: July 2005

Keywords provided by St. Antonius Hospital:
COPD
cytokines
corticosteroids
beta agonists
synergistic effect