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Investigation on the Role of Corticosteroids and Beta-Agonists on Cytokine Production in COPD Patients

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified July 2005 by St. Antonius Hospital.
Recruitment status was:  Recruiting
Information provided by:
St. Antonius Hospital Identifier:
First received: December 7, 2005
Last updated: September 8, 2006
Last verified: July 2005
Research on the synergistic effect of corticosteroids and beta-agonists on the cytokine production in COPD patients. Blood will be obtained from healthy volunteers and COPD patients and blood monocytes will be stimulated to produce cytokines with or without the prementioned drugs.


Study Type: Observational
Study Design: Observational Model: Case Control
Primary Purpose: Screening
Time Perspective: Longitudinal
Time Perspective: Prospective
Official Title: Experimental Study on the Role of Corticosteroids and Beta-Agonists on Cytokine Production in COPD Patients

Resource links provided by NLM:

Further study details as provided by St. Antonius Hospital:

Estimated Enrollment: 90
Study Start Date: October 2005

Ages Eligible for Study:   40 Years and older   (Adult, Senior)
Genders Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • clinical COPD
  • smoking
  • age > 40 years

Exclusion Criteria:

  • age < 40 years
  • use of antibiotics, corticosteroids or beta-agonists
  Contacts and Locations
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Please refer to this study by its identifier: NCT00263380

St Antonius Hospital
Nieuwegein, Utrecht, Netherlands, 3435 CM
Sponsors and Collaborators
St. Antonius Hospital
Principal Investigator: Robert Ten Broeke, Dr St. Antonius Hospital
  More Information Identifier: NCT00263380     History of Changes
Other Study ID Numbers: COPD IL8 
Study First Received: December 7, 2005
Last Updated: September 8, 2006
Health Authority: Netherlands: The Central Committee on Research Involving Human Subjects (CCMO)

Keywords provided by St. Antonius Hospital:
beta agonists
synergistic effect processed this record on January 14, 2017