Investigation of Genetic Risk of Cardiovascular Disease in Prospective Cohort Study

The recruitment status of this study is unknown because the information has not been verified recently.
Verified September 2007 by Nagoya University.
Recruitment status was  Recruiting
Aichi Gakuin University
Information provided by:
Nagoya University Identifier:
First received: December 6, 2005
Last updated: September 20, 2007
Last verified: September 2007

Cardiovascular disease is a complex multifactorial and polygenic disorder that is thought to result from an interaction between a person's genetic make up and various environmental factors. Although many studies have revealed that several genetic variants increase the risk of cardiovascular disease, the results of these studies remain controversial. The purpose of this study is to identify polymorphisms that confer susceptibility to cardiovascular disease and to clarify the adequacy of reported susceptibility gene polymorphisms. To complete this purpose, we will prospectively study over 5,000 local residents in whom relationship between these polymorphisms and occurrence of cardiovascular disease over 5 years.

Coronary Disease
Myocardial Infarction
Cerebral Infarction

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Longitudinal
Official Title: Investigation of Genetic Risk of Cardiovascular Disease in Prospective Cohort Study, the Kitanagoya Genome (KING) Study for the Local Residents of Kitanagoya, Japan

Further study details as provided by Nagoya University:

Estimated Enrollment: 7000
Study Start Date: May 2005

Ages Eligible for Study:   50 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Healthy subjects who undergo community-based annual health check in Kitanagoya city
  Contacts and Locations
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Please refer to this study by its identifier: NCT00262691

Contact: Mitsuhiro Yokota, MD, PhD +81-52-759-2111 ext 369
Contact: Mitsuhiro Yokota, MD, PhD +81-52-744-5515

Department of Genome Science, School of Dentistry, Aichi-Gakuin University Recruiting
Nagoya, Aichi, Japan, 464-8651
Contact: Mitsuhiro Yokota, MD, PhD    +81-52-759-2111 ext 369   
Principal Investigator: Mitsuhiro Yokota, MD, PhD         
Sponsors and Collaborators
Nagoya University
Aichi Gakuin University
Study Chair: Mitsuhiro Yokota, MD, PhD Department of Genome Science, School o Dentistry, Aichi-Gakuin University
  More Information

No publications provided by Nagoya University

Additional publications automatically indexed to this study by Identifier (NCT Number): Identifier: NCT00262691     History of Changes
Other Study ID Numbers: NU-05-G-0001
Study First Received: December 6, 2005
Last Updated: September 20, 2007
Health Authority: Japan: Ministry of Health, Labor and Welfare

Additional relevant MeSH terms:
Cardiovascular Diseases
Cerebral Infarction
Coronary Artery Disease
Coronary Disease
Myocardial Infarction
Arterial Occlusive Diseases
Brain Diseases
Brain Infarction
Brain Ischemia
Central Nervous System Diseases
Cerebrovascular Disorders
Heart Diseases
Myocardial Ischemia
Nervous System Diseases
Pathologic Processes
Vascular Diseases processed this record on October 09, 2015