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Investigation of Genetic Risk of Cardiovascular Disease in Prospective Cohort Study

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified September 2007 by Nagoya University.
Recruitment status was:  Recruiting
Aichi Gakuin University
Information provided by:
Nagoya University Identifier:
First received: December 6, 2005
Last updated: September 20, 2007
Last verified: September 2007
Cardiovascular disease is a complex multifactorial and polygenic disorder that is thought to result from an interaction between a person's genetic make up and various environmental factors. Although many studies have revealed that several genetic variants increase the risk of cardiovascular disease, the results of these studies remain controversial. The purpose of this study is to identify polymorphisms that confer susceptibility to cardiovascular disease and to clarify the adequacy of reported susceptibility gene polymorphisms. To complete this purpose, we will prospectively study over 5,000 local residents in whom relationship between these polymorphisms and occurrence of cardiovascular disease over 5 years.

Healthy Coronary Disease Myocardial Infarction Cerebral Infarction

Study Type: Observational
Study Design: Observational Model: Case Control
Observational Model: Natural History
Time Perspective: Longitudinal
Time Perspective: Prospective
Official Title: Investigation of Genetic Risk of Cardiovascular Disease in Prospective Cohort Study, the Kitanagoya Genome (KING) Study for the Local Residents of Kitanagoya, Japan

Further study details as provided by Nagoya University:

Estimated Enrollment: 7000
Study Start Date: May 2005

Ages Eligible for Study:   50 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Healthy subjects who undergo community-based annual health check in Kitanagoya city
  Contacts and Locations
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Please refer to this study by its identifier: NCT00262691

Contact: Mitsuhiro Yokota, MD, PhD +81-52-759-2111 ext 369
Contact: Mitsuhiro Yokota, MD, PhD +81-52-744-5515

Department of Genome Science, School of Dentistry, Aichi-Gakuin University Recruiting
Nagoya, Aichi, Japan, 464-8651
Contact: Mitsuhiro Yokota, MD, PhD    +81-52-759-2111 ext 369   
Principal Investigator: Mitsuhiro Yokota, MD, PhD         
Sponsors and Collaborators
Nagoya University
Aichi Gakuin University
Study Chair: Mitsuhiro Yokota, MD, PhD Department of Genome Science, School o Dentistry, Aichi-Gakuin University
  More Information

Publications automatically indexed to this study by Identifier (NCT Number): Identifier: NCT00262691     History of Changes
Other Study ID Numbers: NU-05-G-0001
Study First Received: December 6, 2005
Last Updated: September 20, 2007

Additional relevant MeSH terms:
Cardiovascular Diseases
Myocardial Infarction
Coronary Disease
Coronary Artery Disease
Cerebral Infarction
Pathologic Processes
Myocardial Ischemia
Heart Diseases
Vascular Diseases
Arterial Occlusive Diseases
Brain Infarction
Brain Ischemia
Cerebrovascular Disorders
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Stroke processed this record on September 21, 2017