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Utilization of the Community Popular Opinion Leader (C-POL) Model in Alabama

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ClinicalTrials.gov Identifier: NCT00260754
Recruitment Status : Completed
First Posted : December 2, 2005
Last Update Posted : May 31, 2006
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Study Description
Brief Summary:
Community members within the treatment city will report: 1)engaging in fewer sexual risk practices; 2)significantly higher condom use; 3) significantly higher rates of STD care seeking (including STD screening behaviors); 4) fewer having STDs in the past 6 months; 5) significantly higher awareness scores regarding syphilis and other STDs, as compared with those in the comparison city.

Condition or disease Intervention/treatment
Risk Behavior Sexually Transmitted Diseases Behavioral: Community-Popular Opinion Leader Model Behavioral: Diffusion of Innovations

Detailed Description:

The C-POL in Alabama project is and intervention study which sought to impact the health behaviors of community residents who live in zip codes that have high syphilis morbidity. The study is being implemented in Birmingham and Montgomery with shelter clients.

The intervention model used for this study is the Popular Opinion Leader (POL) model, which is effective at reducing new HIV infections. The intent of this study was to determine the effectiveness of a diffusion model (e.g. POL) at reducing syphilis infections in affected communities.

For the intervention, community members identified as popular opinion leaders were recruited and trained to share accurate information about syphilis transmission, symptoms, testing, treatment and prevention. Prior to intervention implementation and several times after, community members were given a survey and screened for syphilis as well as 2-3 additional STDs. During each assessment, cross-sections of the community members were sampled.

Study Design

Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 600 participants
Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: None (Open Label)
Primary Purpose: Prevention
Official Title: Utilization of the Community Popular Opinion Leader (C-POL) Model to Achieve Syphilis Elimination in Alabama
Study Start Date : October 2002
Estimated Study Completion Date : July 2005

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U.S. FDA Resources

Arms and Interventions

Outcome Measures

Primary Outcome Measures :
  1. Changes in syphilis morbidity in affected community

Secondary Outcome Measures :
  1. Changes in risk behavior and health care seeking behavior

Eligibility Criteria

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Clients who utilized two community homeless shelters in the affected community. The affected community was one that had significant syphilis morbidity at the onset of the study.

Exclusion Criteria:

Contacts and Locations

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To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00260754

United States, Alabama
University of Alabama, Birmingham
Birmingham, Alabama, United States, 35294-0022
Sponsors and Collaborators
Centers for Disease Control and Prevention
University of Alabama at Birmingham
Study Chair: Samantha Williams, Ph.D. CDC/NCHSTP/DSTDP/BIRB
Principal Investigator: Diane Grimley, Ph.D. University of Alabama at Birmingham
More Information

ClinicalTrials.gov Identifier: NCT00260754     History of Changes
Other Study ID Numbers: CDC-NCHSTP-4087
First Posted: December 2, 2005    Key Record Dates
Last Update Posted: May 31, 2006
Last Verified: December 2005

Keywords provided by Centers for Disease Control and Prevention:
Risk behavior
Sexually transmitted diseases

Additional relevant MeSH terms:
Sexually Transmitted Diseases
Virus Diseases
Genital Diseases, Male
Genital Diseases, Female