This study attempts to test capillary responses to various challenges without the need for iontophoresis (electrical current).
Device: Laser Doppler Flowmetry with topical acetylcholine and nitroglycerin
|Study Design:||Observational Model: Defined Population
Primary Purpose: Screening
Time Perspective: Cross-Sectional
|Official Title:||Transdermal Application of Acetylcholine and Nitroglycerin Without Iontophoresis.|
|Study Start Date:||June 2005|
|Estimated Study Completion Date:||September 2005|
Studies of microvascular responsiveness often employ iontophoresis to fascilitate drug absorption. Iontophoresis is a confounding stimulus in such studies, and we are attempting to create tests of the microvasculature that do not require iontophoretic drug delivery.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00259701
|United States, Connecticut|
|Yale School of Medicine|
|New HAven, Connecticut, United States, 06510|
|Principal Investigator:||David G Silverman||Yale School of Medicine|