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This study is designed to determine if the use of atorvastatin (Lipitor), a member of the HMG coA reductase inhibitor class of drugs referred to as statins, will reduce inflammatory responses and deep vein thrombosis formation when given in high doses in the perioperative period.
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Ages Eligible for Study:
18 Years and older (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
gynecologic tumor scheduled for resection
prior reaction to statins
prior h/o DVT or hypercoagulability
concurrent medications that significantly affect cytochrome P450 3A4