Evaluation of Take and Safety of a Smallpox Vaccine in Healthy Young Adults
To estimate the smallpox vaccination take rate in healthy young adults not previously vaccinated with a smallpox vaccine.
To describe antibody response to vaccination and evaluate the take for each subject at various timepoints for each batch and pooled batches and to evaluate local signs, symptoms, and overall safety in healthy young adults not previously vaccinated with a smallpox vaccine.
Biological: Smallpox vaccine, LISTER strain, from chick embryo cells
|Study Design:||Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor)
Primary Purpose: Prevention
|Official Title:||Take Evaluation and Safety of Smallpox Vaccine (LISTER Strain) in Naïve Healthy Adults.|
Please refer to this study by its ClinicalTrials.gov identifier: NCT00258947
|Study Director:||Medical Director||Sanofi Pasteur Inc|