Effects of Pretreatment With Ibuprofen in Post-Electroconvulsive Therapy (ECT) Headache
The purpose of the study is to determine whether ibuprofen reduces post-ECT headache or reduces its severity.
|Study Design:||Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Crossover Assignment
Masking: Double Blind (Subject, Outcomes Assessor)
Primary Purpose: Treatment
|Official Title:||Effects of Pretreatment With Ibuprofen in Post- ECT Headache|
|Study Start Date:||January 2012|
|Study Completion Date:||May 2012|
|Primary Completion Date:||May 2012 (Final data collection date for primary outcome measure)|
The aim of the study is to compare the severity of headache between patients who are receiving ibuprofen prior to ECT treatment with patients receiving placebo prior to ECT treatment.
Patients will be randomly assigned to receive either 600 mg ibuprofen 90 min prior to treatment or placebo orally, blinded to patient, physician and treatment team.
Patients will be asked about their headache with a visual analogue scale (VAS) 2 hours prior to and within 2 hours after treatment, 2-month, 6- month and 1 year follow-up .
Please refer to this study by its ClinicalTrials.gov identifier: NCT00258791
|Principal Investigator:||Olav Morten Linaker, MD PhD||Norwegian University of Science and Technology|