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Respiratory Mechanics and Pleural Effusion

This study has been completed.
Information provided by (Responsible Party):
Davide Chiumello, Policlinico Hospital Identifier:
First received: November 23, 2005
Last updated: March 7, 2012
Last verified: March 2012
The investigators aim to compare the respiratory mechanics in acute lung injury (ALI)/acute respiratory diseases syndrome (ARDS) patients with and without pleural effusion.

Condition Intervention
Critically Ill Acute Lung Injury ARDS Procedure: mechanical ventilation/CT Scan

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Estimation of Respiratory Mechanics (Respiratory System, Chest Wall and Lung Elastance) and Pleural Effusion at the Bedside With CT Scan.

Resource links provided by NLM:

Further study details as provided by Davide Chiumello, Policlinico Hospital:

Primary Outcome Measures:
  • Role of pleural effusion and respiratory mechanics [ Time Frame: 1 hour ]

Enrollment: 60
Study Start Date: November 2005
Study Completion Date: June 2011
Primary Completion Date: June 2011 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
ALI/ARDS patients
Procedure: mechanical ventilation/CT Scan
evaluation of pleural effusion and respiratory mechanics, CT scan

Detailed Description:
In ALI/ARDS we evaluated the respiratory mechanics (respiratory system, chest wall and lung elastance) at the bedside while pleural effusion was evaluated with CT scan. Thus we will be able to estimate any possible role of pleural effusion on the respiratory mechanics.

Ages Eligible for Study:   16 Years to 90 Years   (Child, Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
ALI/ARDS patients

Inclusion Criteria:

  • ALI/ARDS patients underwent invasive mechanical ventilation

Exclusion Criteria:

  • Haemodynamic instability
  • Chronic obstructive pulmonary disease (COPD) patients
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Please refer to this study by its identifier: NCT00258518

Policlinico Hospital
Milano, Italy, 20122
Sponsors and Collaborators
Policlinico Hospital
Principal Investigator: Davide Chiumello, MD Policlinico Hospital
  More Information

Responsible Party: Davide Chiumello, MD, Policlinico Hospital Identifier: NCT00258518     History of Changes
Other Study ID Numbers: 1500
Study First Received: November 23, 2005
Last Updated: March 7, 2012

Keywords provided by Davide Chiumello, Policlinico Hospital:
Critically ill patients

Additional relevant MeSH terms:
Critical Illness
Lung Injury
Pleural Effusion
Acute Lung Injury
Respiratory Distress Syndrome, Adult
Disease Attributes
Pathologic Processes
Lung Diseases
Respiratory Tract Diseases
Thoracic Injuries
Wounds and Injuries
Pleural Diseases
Respiration Disorders processed this record on August 16, 2017