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Respiratory Mechanics and Pleural Effusion

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ClinicalTrials.gov Identifier: NCT00258518
Recruitment Status : Completed
First Posted : November 24, 2005
Last Update Posted : March 8, 2012
Information provided by (Responsible Party):
Davide Chiumello, Policlinico Hospital

Brief Summary:
The investigators aim to compare the respiratory mechanics in acute lung injury (ALI)/acute respiratory diseases syndrome (ARDS) patients with and without pleural effusion.

Condition or disease Intervention/treatment
Critically Ill Acute Lung Injury ARDS Procedure: mechanical ventilation/CT Scan

Detailed Description:
In ALI/ARDS we evaluated the respiratory mechanics (respiratory system, chest wall and lung elastance) at the bedside while pleural effusion was evaluated with CT scan. Thus we will be able to estimate any possible role of pleural effusion on the respiratory mechanics.

Study Type : Observational
Actual Enrollment : 60 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Estimation of Respiratory Mechanics (Respiratory System, Chest Wall and Lung Elastance) and Pleural Effusion at the Bedside With CT Scan.
Study Start Date : November 2005
Primary Completion Date : June 2011
Study Completion Date : June 2011

Group/Cohort Intervention/treatment
ALI/ARDS patients
Procedure: mechanical ventilation/CT Scan
evaluation of pleural effusion and respiratory mechanics, CT scan

Primary Outcome Measures :
  1. Role of pleural effusion and respiratory mechanics [ Time Frame: 1 hour ]

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Ages Eligible for Study:   16 Years to 90 Years   (Child, Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
ALI/ARDS patients

Inclusion Criteria:

  • ALI/ARDS patients underwent invasive mechanical ventilation

Exclusion Criteria:

  • Haemodynamic instability
  • Chronic obstructive pulmonary disease (COPD) patients

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00258518

Policlinico Hospital
Milano, Italy, 20122
Sponsors and Collaborators
Policlinico Hospital
Principal Investigator: Davide Chiumello, MD Policlinico Hospital

Responsible Party: Davide Chiumello, MD, Policlinico Hospital
ClinicalTrials.gov Identifier: NCT00258518     History of Changes
Other Study ID Numbers: 1500
First Posted: November 24, 2005    Key Record Dates
Last Update Posted: March 8, 2012
Last Verified: March 2012

Keywords provided by Davide Chiumello, Policlinico Hospital:
Critically ill patients

Additional relevant MeSH terms:
Critical Illness
Lung Injury
Pleural Effusion
Acute Lung Injury
Respiratory Distress Syndrome, Adult
Disease Attributes
Pathologic Processes
Lung Diseases
Respiratory Tract Diseases
Thoracic Injuries
Wounds and Injuries
Pleural Diseases
Respiration Disorders