Outcome of Postnatal Depression Screening Using Edinburgh Postnatal Depression Scale

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00251342
Recruitment Status : Unknown
Verified April 2007 by Chinese University of Hong Kong.
Recruitment status was:  Recruiting
First Posted : November 10, 2005
Last Update Posted : April 5, 2007
Hong Kong Department of Health
The University of Hong Kong
Information provided by:
Chinese University of Hong Kong

Brief Summary:
The objective of the present study is to evaluate the effectiveness of postnatal depression screening by comparing the mental health outcome (at 6 months postpartum) of mothers under the Edinburgh Postnatal Depression Scale (EPDS) screening programme versus usual clinical practice (usual practice), using randomized controlled trial design. With the use of the EPDS for the screening of postnatal depression, it is expected that more mothers in need of intervention (including mental health intervention, guidance in childcare and parenting, counseling in family relationships, etc) will be picked up and offered appropriate intervention, compared to the usual practice. It is hypothesized that the mental health of the group of women under the EPDS screening programme will be better than those under the usual practice, on subsequent follow-up.

Condition or disease Intervention/treatment Phase
Depression, Postpartum Procedure: Edinburgh Postnatal Depression Scale Phase 2 Phase 3

Study Type : Interventional  (Clinical Trial)
Enrollment : 460 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double
Primary Purpose: Diagnostic
Official Title: Outcome of Postnatal Depression Screening Using Edinburgh Postnatal Depression Scale
Study Start Date : October 2005
Estimated Study Completion Date : January 2008

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Primary Outcome Measures :
  1. Mother's mental health at 6 months postpartum, as measured on the EPDS and General Health Questionnaire-12 (GHQ-12), both being self-report questionnaires.

Secondary Outcome Measures :
  1. Mother's parenting stress (measured by the Parenting Stress Index, a self-report questionnaire)
  2. Marital relationship satisfaction (measured by the Chinese Kansas Marital Satisfaction Scale, a self-report questionnaire)
  3. Marital status and employment status (both father and mother, where applicable) at 6 and 18 months postpartum
  4. Child health measures, including weight at 6 and 18 months, number of hospitalizations and visits to doctors within the first 6 and 18 months as reported by mother
  5. Mother's mental health outcome (EPDS and GHQ scores) at 18 months postpartum

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  1. Chinese mothers of newborn babies <= 2 months who are registered with the 4 Maternal and Child Health Centres under study;
  2. Normally resident in Hong Kong (Hong Kong ID card holder, or HK Birth Certificate [with status of permanent resident indicated established] holder, or people who have been granted unconditional stay in Hong Kong, or passport holders having valid travel document showing the right to land in Hong Kong, or permission to land, or eligibility of HK permanent ID card verified, or entitlement to the right of abode in HK)

Exclusion Criteria:

  1. Those who do not use the Chinese language (in both the written and spoken form);
  2. Those who are under active psychiatric contact;
  3. Those who delivered in hospitals which are still conducting their own EPDS screening programme.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00251342

Contact: Cynthia Leung

Maternal and Child Health Centres, Department of Health Recruiting
Hong Kong, China
Contact: Cynthia Leung   
Sponsors and Collaborators
Chinese University of Hong Kong
Hong Kong Department of Health
The University of Hong Kong
Principal Investigator: Dominic TS Lee, M.D. Department of Psychiatry, The Chinese University of Hong Kong
Principal Investigator: Shirley SL Leung, MPH Family Health Service, Department of Health, HKSAR

Publications automatically indexed to this study by Identifier (NCT Number): Identifier: NCT00251342     History of Changes
Other Study ID Numbers: CRE-2005.224-T
First Posted: November 10, 2005    Key Record Dates
Last Update Posted: April 5, 2007
Last Verified: April 2007

Keywords provided by Chinese University of Hong Kong:
Postnatal depression
Randomized controlled trial
Edinburgh Postnatal Depression Scale

Additional relevant MeSH terms:
Depressive Disorder
Depression, Postpartum
Behavioral Symptoms
Mood Disorders
Mental Disorders
Puerperal Disorders
Pregnancy Complications