VX-950 and Peginterferon for Hepatitis C

This study has been completed.
Information provided by:
Vertex Pharmaceuticals Incorporated
ClinicalTrials.gov Identifier:
First received: November 7, 2005
Last updated: December 17, 2007
Last verified: December 2007
VX-950 is an investigational drug , which is being tested in combination with a known treatment for hepatitis C, peginterferon.

Condition Intervention Phase
Hepatitis C
Drug: VX-950
Drug: peginterferon
Phase 1

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double-Blind
Official Title: A Phase 1b Viral Kinetic Study of VX-950 and Peginterferon in Hepatitis C

Resource links provided by NLM:

Further study details as provided by Vertex Pharmaceuticals Incorporated:

Primary Outcome Measures:
  • Viral kinetics

Secondary Outcome Measures:
  • Assess the safety of VX-950 in combination with peginterferon

Estimated Enrollment: 20
Study Start Date: October 2005
Study Completion Date: March 2006

Ages Eligible for Study:   18 Years to 60 Years
Genders Eligible for Study:   Both

Inclusion Criteria:

  • infected with Hepatitis C virus

Exclusion Criteria:

  • contraindications to peginterferon therapy
  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00251199

Call for information
Homburg/Saar, Germany
Call for information
Amsterdam, Netherlands
Sponsors and Collaborators
Vertex Pharmaceuticals Incorporated
Study Director: Medical Monitor Vertex Pharmaceuticals Incorporated
  More Information

ClinicalTrials.gov Identifier: NCT00251199     History of Changes
Other Study ID Numbers: VX05-950-103 
Study First Received: November 7, 2005
Last Updated: December 17, 2007
Health Authority: Germany: Federal Institute for Drugs and Medical Devices

Additional relevant MeSH terms:
Hepatitis A
Hepatitis C
Digestive System Diseases
Enterovirus Infections
Flaviviridae Infections
Hepatitis, Viral, Human
Liver Diseases
Picornaviridae Infections
RNA Virus Infections
Virus Diseases

ClinicalTrials.gov processed this record on May 04, 2016