VX-950 and Peginterferon for Hepatitis C

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00251199
Recruitment Status : Completed
First Posted : November 9, 2005
Last Update Posted : December 21, 2007
Information provided by:
Vertex Pharmaceuticals Incorporated

Brief Summary:
VX-950 is an investigational drug , which is being tested in combination with a known treatment for hepatitis C, peginterferon.

Condition or disease Intervention/treatment Phase
Hepatitis C Drug: VX-950 Drug: peginterferon Phase 1

Study Type : Interventional  (Clinical Trial)
Enrollment : 20 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double
Official Title: A Phase 1b Viral Kinetic Study of VX-950 and Peginterferon in Hepatitis C
Study Start Date : October 2005
Actual Study Completion Date : March 2006

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Primary Outcome Measures :
  1. Viral kinetics

Secondary Outcome Measures :
  1. Assess the safety of VX-950 in combination with peginterferon

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 60 Years   (Adult)
Sexes Eligible for Study:   All

Inclusion Criteria:

  • infected with Hepatitis C virus

Exclusion Criteria:

  • contraindications to peginterferon therapy

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00251199

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Homburg/Saar, Germany
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Amsterdam, Netherlands
Sponsors and Collaborators
Vertex Pharmaceuticals Incorporated
Study Director: Medical Monitor Vertex Pharmaceuticals Incorporated Identifier: NCT00251199     History of Changes
Other Study ID Numbers: VX05-950-103
First Posted: November 9, 2005    Key Record Dates
Last Update Posted: December 21, 2007
Last Verified: December 2007

Additional relevant MeSH terms:
Hepatitis A
Hepatitis C
Liver Diseases
Digestive System Diseases
Hepatitis, Viral, Human
Virus Diseases
Enterovirus Infections
Picornaviridae Infections
RNA Virus Infections
Flaviviridae Infections