DOCICAR: Cardiac Dysfunction in Cirrhosis

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00250315
Recruitment Status : Completed
First Posted : November 8, 2005
Last Update Posted : November 1, 2007
Information provided by:
Hvidovre University Hospital

Brief Summary:
Patients with cirrhosis have a altered cardiac response to stress. This study evaluate the cardiac response by MRI during dobutamine stress. Hypothesis: impared increase in cardiac output, cardiac index, ejection fraction.

Condition or disease Intervention/treatment
Cirrhosis Cirrhotic Cardiomyopathy Drug: Dobutamine

Study Type : Observational
Time Perspective: Prospective
Official Title: Cardiac Dysfunction in Cirrhosis: Cirrhotic Cardiomyopathy Evaluated by Dobutamin MRI.
Study Start Date : November 2005
Actual Study Completion Date : October 2007

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Ages Eligible for Study:   18 Years to 75 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Non alkoholic cirrhosis

Exclusion Criteria:

  • Coma hepaticum
  • Primary cardiac diseases

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00250315

Hvidovre University Hospital
Copenhagen, Hvidovre, Denmark, 2650
Sponsors and Collaborators
Hvidovre University Hospital
Study Director: Søren Møller, DrMsci, MD Hvidovre University Hospital

Publications automatically indexed to this study by Identifier (NCT Number): Identifier: NCT00250315     History of Changes
Other Study ID Numbers: (KF) 01 270675
First Posted: November 8, 2005    Key Record Dates
Last Update Posted: November 1, 2007
Last Verified: October 2007

Additional relevant MeSH terms:
Liver Cirrhosis
Pathologic Processes
Liver Diseases
Digestive System Diseases
Heart Diseases
Cardiovascular Diseases
Cardiotonic Agents
Autonomic Agents
Peripheral Nervous System Agents
Physiological Effects of Drugs
Adrenergic beta-1 Receptor Agonists
Adrenergic beta-Agonists
Adrenergic Agonists
Adrenergic Agents
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action
Protective Agents