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Vouchers vs. Prizes for Cocaine-Dependent Methadone Patients - 2

This study has been completed.
National Institute on Drug Abuse (NIDA)
Information provided by (Responsible Party):
UConn Health Identifier:
First received: November 3, 2005
Last updated: March 29, 2012
Last verified: March 2012
The purpose of this study is to compare voucher-based contingency management (CM) procedures to a lower-cost CM system that provides opportunities to win prizes. Cocaine-dependent outpatients are randomly assigned to (a) standard treatment, (b) standard treatment plus usual magnitude prize CM, (c) standard treatment plus higher magnitude prize CM, or (d) standard treatment plus voucher CM. Urine and breath samples are collected 2-3x/week for 14 weeks. Follow-up interviews are conducted at 1,3,6 and 9 months following intake during which substance use and psychosocial functioning are assessed.

Condition Intervention
Cocaine Dependence
Behavioral: Contingency management

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Vouchers vs. Prizes for Cocaine-Dependent Methadone Patients

Resource links provided by NLM:

Further study details as provided by UConn Health:

Primary Outcome Measures:
  • Cocaine use [ Time Frame: baseline and each follow-up ]

Enrollment: 240
Study Start Date: March 2005
Study Completion Date: July 2011
Primary Completion Date: July 2011 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 1
standard treatment plus usual magnitude prize CM
Behavioral: Contingency management
Rewards (prizes) for abstinence
Experimental: 2
standard treatment plus higher magnitude prize CM
Behavioral: Contingency management
Rewards (prizes) for abstinence
Experimental: 3
standard treatment plus voucher CM
Behavioral: Contingency management
Rewards (prizes) for abstinence


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion criteria:

  • age > 18 years
  • current DSM-IV diagnosis of cocaine dependence
  • received methadone treatment at the clinic for at least 3 months
  • on a stable dose of methadone (no changes in dosing) for at least one month and not presently requesting a dose alteration
  • submitted one or more clinic-collected cocaine positive urine samples in the previous 3 months
  • English speaking
  • pass a brief quiz related to understanding of the informed consent form

Exclusion criteria:

  • have a serious, uncontrolled psychiatric illness (e.g., acute schizophrenia, bipolar disorder, severe or psychotic major depression, or suicide risk)
  • have dementia (<23 on the Mini Mental State Exam; Folstein et al. 1975)
  • are in recovery from pathological gambling
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Please refer to this study by its identifier: NCT00249535

United States, Connecticut
UConn Health Center
Farmington, Connecticut, United States, 06030
Sponsors and Collaborators
UConn Health
National Institute on Drug Abuse (NIDA)
Principal Investigator: Nancy Petry, Ph.D. UConn Health
  More Information

Responsible Party: UConn Health Identifier: NCT00249535     History of Changes
Other Study ID Numbers: NIDA-13444-2
R01DA013444 ( US NIH Grant/Contract Award Number )
Study First Received: November 3, 2005
Last Updated: March 29, 2012

Keywords provided by UConn Health:
Substance Abuse
Contingency Management

Additional relevant MeSH terms:
Cocaine-Related Disorders
Substance-Related Disorders
Chemically-Induced Disorders
Mental Disorders
Analgesics, Opioid
Central Nervous System Depressants
Physiological Effects of Drugs
Sensory System Agents
Peripheral Nervous System Agents
Antitussive Agents
Respiratory System Agents
Anesthetics, Local
Vasoconstrictor Agents
Dopamine Uptake Inhibitors
Neurotransmitter Uptake Inhibitors
Membrane Transport Modulators
Molecular Mechanisms of Pharmacological Action
Dopamine Agents
Neurotransmitter Agents processed this record on May 25, 2017