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Vouchers vs. Prizes for Cocaine-Dependent Methadone Patients - 2

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00249535
First Posted: November 7, 2005
Last Update Posted: March 30, 2012
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Collaborator:
National Institute on Drug Abuse (NIDA)
Information provided by (Responsible Party):
UConn Health
  Purpose
The purpose of this study is to compare voucher-based contingency management (CM) procedures to a lower-cost CM system that provides opportunities to win prizes. Cocaine-dependent outpatients are randomly assigned to (a) standard treatment, (b) standard treatment plus usual magnitude prize CM, (c) standard treatment plus higher magnitude prize CM, or (d) standard treatment plus voucher CM. Urine and breath samples are collected 2-3x/week for 14 weeks. Follow-up interviews are conducted at 1,3,6 and 9 months following intake during which substance use and psychosocial functioning are assessed.

Condition Intervention
Cocaine Dependence Behavioral: Contingency management

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Vouchers vs. Prizes for Cocaine-Dependent Methadone Patients

Resource links provided by NLM:


Further study details as provided by UConn Health:

Primary Outcome Measures:
  • Cocaine use [ Time Frame: baseline and each follow-up ]

Enrollment: 240
Study Start Date: March 2005
Study Completion Date: July 2011
Primary Completion Date: July 2011 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 1
standard treatment plus usual magnitude prize CM
Behavioral: Contingency management
Rewards (prizes) for abstinence
Experimental: 2
standard treatment plus higher magnitude prize CM
Behavioral: Contingency management
Rewards (prizes) for abstinence
Experimental: 3
standard treatment plus voucher CM
Behavioral: Contingency management
Rewards (prizes) for abstinence

  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion criteria:

  • age > 18 years
  • current DSM-IV diagnosis of cocaine dependence
  • received methadone treatment at the clinic for at least 3 months
  • on a stable dose of methadone (no changes in dosing) for at least one month and not presently requesting a dose alteration
  • submitted one or more clinic-collected cocaine positive urine samples in the previous 3 months
  • English speaking
  • pass a brief quiz related to understanding of the informed consent form

Exclusion criteria:

  • have a serious, uncontrolled psychiatric illness (e.g., acute schizophrenia, bipolar disorder, severe or psychotic major depression, or suicide risk)
  • have dementia (<23 on the Mini Mental State Exam; Folstein et al. 1975)
  • are in recovery from pathological gambling
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00249535


Locations
United States, Connecticut
UConn Health Center
Farmington, Connecticut, United States, 06030
Sponsors and Collaborators
UConn Health
National Institute on Drug Abuse (NIDA)
Investigators
Principal Investigator: Nancy Petry, Ph.D. UConn Health
  More Information

Responsible Party: UConn Health
ClinicalTrials.gov Identifier: NCT00249535     History of Changes
Other Study ID Numbers: NIDA-13444-2
R01DA013444 ( U.S. NIH Grant/Contract )
First Submitted: November 3, 2005
First Posted: November 7, 2005
Last Update Posted: March 30, 2012
Last Verified: March 2012

Keywords provided by UConn Health:
Substance Abuse
Contingency Management

Additional relevant MeSH terms:
Cocaine-Related Disorders
Substance-Related Disorders
Chemically-Induced Disorders
Mental Disorders
Methadone
Cocaine
Analgesics, Opioid
Narcotics
Central Nervous System Depressants
Physiological Effects of Drugs
Analgesics
Sensory System Agents
Peripheral Nervous System Agents
Antitussive Agents
Respiratory System Agents
Anesthetics, Local
Anesthetics
Vasoconstrictor Agents
Dopamine Uptake Inhibitors
Neurotransmitter Uptake Inhibitors
Membrane Transport Modulators
Molecular Mechanisms of Pharmacological Action
Dopamine Agents
Neurotransmitter Agents