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Trial record 46 of 1224 for:    arthritis+management

Improving Motivation for Physical Activity in Arthritis Clinical Trial (IMPAACT)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00248105
Recruitment Status : Completed
First Posted : November 3, 2005
Last Update Posted : November 4, 2013
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Information provided by (Responsible Party):
Rowland W. Chang, Northwestern University

Brief Summary:

Arthritis is a major cause of disability. Of the nearly 70 million persons in the US with arthritis and/or chronic joint symptoms, nearly 8 million are disabled because of their arthritis. Knee osteoarthritis (OA) and rheumatoid arthritis (RA) are two of its most common and disabling forms. Despite evidence that physical activity can improve functional and health related quality of life (HRQOL) outcomes and lower health care costs, the proportion of the US population engaging in the recommended amount of physical activity is low and even lower among those with arthritis. Moreover, there is considerable variation in clinicians' promotion of physical activity for arthritis clients. Care providers infrequently ask clients about their physical activity behavior and report feeling unprepared to promote physical activity.

This application studies the effects of a behavioral intervention aimed at promoting physical activity, including lifestyle physical activity, on arthritis-specific and generic HRQOL outcomes. The proposed physical activity management program (PAM) is based on a chronic care model in which allied health professionals promote patient self-management activities outside of traditional physician office encounters. The program is an individualized counseling and referral intervention, conducted by physical activity managers, directed by a theory-based comprehensive assessment of individual patient barriers and strengths related to physical activity performance. The specific aims of this randomized, controlled trial of 480 clients with RA and knee OA followed for 24 months are to test the effectiveness of physical activity management combined with physician physical activity promotion (PAM group) compared to physician physical activity promotion only (control group) in improving arthritis-specific and generic HRQOL, observed measures of function, and objectively measured and self-reported physical activity levels. In addition, exploratory analyses will be done to assess whether the improvements in HRQOL and physical activity performance associated with the PAM program are mediated by increases in physical activity levels and theory-based motivational variables, respectively. This study is intended to generate feasible methods by which health care providers and health care systems can increase physical activity levels in clients with arthritis and to result in widely applicable strategies for health behavior change.

Condition or disease Intervention/treatment Phase
Osteoarthritis, Knee Rheumatoid Arthritis Behavioral: Lifestyle Physical Activity Management Not Applicable

  Show Detailed Description

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 889 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Physical Activity in Persons With Arthritis
Study Start Date : September 2005
Actual Primary Completion Date : August 2010
Actual Study Completion Date : August 2010

Resource links provided by the National Library of Medicine

Arm Intervention/treatment
Experimental: PAM Behavioral: Lifestyle Physical Activity Management
Lifestyle Physical Activity Promotion as given by Physical Activity Advocates. Advocates will meet with participants at baseline and every 3 months throughout the study to promote increase in lifestyle physical activity reached through goal setting and Motivational Interviewing (MI)

No Intervention: PC
Participants not in the PAM group will be in the PC (physician counseling) group and will receive advice on lifestyle physical activity from their rheumatologist or primary care physician.

Primary Outcome Measures :
  1. Function [ Time Frame: 2 years ]

Secondary Outcome Measures :
  1. Quality of Life [ Time Frame: 2 years ]

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • 18 yrs. or older
  • ACR criteria for KOA or RA
  • Able to speak and read English
  • Able to ambulate at least household distances

Exclusion Criteria:

  • Planned total joint replacement surgery in the next 2 years
  • Contraindication to physical activity due to co-morbid condition
  • Unable to perform basic self-care (functional class IV) or walk household distances
  • Planned Relocation away from Chicago area in next two years

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00248105

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United States, Illinois
Chicago, Illinois, United States, 60611
Rehabilitation Institute Of Chicago
Chicago, Illinois, United States, 60611
Sponsors and Collaborators
Northwestern University
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
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Principal Investigator: Rowland W. Chang, MD MPH Northwestern University Feinberg School of Medicine

Publications automatically indexed to this study by Identifier (NCT Number):
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Responsible Party: Rowland W. Chang, Professor of Preventive Medicine, Medicine, and Physical Medicine & Rehabilitation, Northwestern University Identifier: NCT00248105     History of Changes
Other Study ID Numbers: 1R01AR052912-01 ( U.S. NIH Grant/Contract )
R01AR052912-01 ( U.S. NIH Grant/Contract )
First Posted: November 3, 2005    Key Record Dates
Last Update Posted: November 4, 2013
Last Verified: October 2013

Keywords provided by Rowland W. Chang, Northwestern University:
Physical Activity

Additional relevant MeSH terms:
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Arthritis, Rheumatoid
Osteoarthritis, Knee
Joint Diseases
Musculoskeletal Diseases
Rheumatic Diseases
Connective Tissue Diseases
Autoimmune Diseases
Immune System Diseases