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Adherence of Stalevo, Entacapone and Levodopa
This study has been completed.
Sponsor:
South Glasgow University Hospitals NHS Trust
Information provided by:
South Glasgow University Hospitals NHS Trust
ClinicalTrials.gov Identifier:
NCT00245700
First received: October 27, 2005
Last updated: May 22, 2008
Last verified: May 2008
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Purpose
To test if combining two antiparkinson drugs into a single tablet improves accuracy of medicine intake by the patient.
To test if patients with Parkinson's disease who take medicines at regular time intervals have smoother symptom control.
| Condition |
|---|
| Parkinson's Disease |
| Study Type: | Observational |
| Official Title: | Study of Adherence of Stalevo, Entacapone and Levodopa |
Resource links provided by NLM:
Genetics Home Reference related topics:
Parkinson disease
MedlinePlus related topics:
Parkinson's Disease
U.S. FDA Resources
Further study details as provided by South Glasgow University Hospitals NHS Trust:
Eligibility| Ages Eligible for Study: | 18 Years to 85 Years (Adult, Senior) |
| Sexes Eligible for Study: | All |
Criteria
Inclusion Criteria:
- Patients diagnosed with Parkinson's disease aged between 18 and 85 years fulfilling UK Brain Bank criteria.
- Current levodopa therapy prescribed on a regular basis three or more times per day but requiring entacapone because of 'wearing off'
- Able to manipulate electronic monitoring bottles and complete questionnaires
Exclusion Criteria:
- Current use of compliance aid such that study participation would be detrimental to patient's adherence
- Pregnancy or breast feeding
- Excess alcohol (over 21 units per week for women and 28 units for men)
- Mini mental state examination of less than 26.
- Severe depression (Geriatric depression score over 20)
Contacts and Locations
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To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below.
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Please refer to this study by its ClinicalTrials.gov identifier: NCT00245700
Please refer to this study by its ClinicalTrials.gov identifier: NCT00245700
Locations
| United Kingdom | |
| Southern General Hospital | |
| Glasgow, Scotland, United Kingdom, G51 4TF | |
Sponsors and Collaborators
South Glasgow University Hospitals NHS Trust
Investigators
| Principal Investigator: | Donald G Grosset, MBChB, MD |
More Information
| Responsible Party: | Dr D Grosset, Southern General Hospital |
| ClinicalTrials.gov Identifier: | NCT00245700 History of Changes |
| Other Study ID Numbers: |
R050017 Grant from Orion Pharma |
| Study First Received: | October 27, 2005 |
| Last Updated: | May 22, 2008 |
Additional relevant MeSH terms:
|
Parkinson Disease Parkinsonian Disorders Basal Ganglia Diseases Brain Diseases Central Nervous System Diseases Nervous System Diseases Movement Disorders Neurodegenerative Diseases Levodopa |
Entacapone Antiparkinson Agents Anti-Dyskinesia Agents Dopamine Agents Neurotransmitter Agents Molecular Mechanisms of Pharmacological Action Physiological Effects of Drugs Catechol O-Methyltransferase Inhibitors Enzyme Inhibitors |
ClinicalTrials.gov processed this record on September 21, 2017