Functional Magnetic Resonance Imaging (fMRI) Study of Memory in Children
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00242905|
Recruitment Status : Completed
First Posted : October 21, 2005
Last Update Posted : May 2, 2011
|Condition or disease||Intervention/treatment|
|Childhood Absence Epilepsy [Pyknolepsy]||Behavioral: Study of memory using MRI|
Twenty children aged from 6 to 18 years with temporal and/or frontal epilepsy and 20 normal children in the same age range will undergo the following examinations in a unique day in the Unit Hospital F. JOLIOT(CEA in ORSAY, France):
- complete neuropsychological evaluation including episodic memory,
- structural MRI to quantify, using VBM, the potential abnormalities of the anatomical structures, to perform cognitive-morphological correlations, and to localize the neuronal networks activated on fMRI,
- functional MRI using an original task of episodic memory, specifically dedicated to children and being under behavioural validation laboratory.
The analysis of fMRI data will be performed using SPM and taking into account the existence of epilepsy or not, of cerebral lesion or not, age, handedness, the side and location of epileptogenic focus, the age of seizure onset, and the type of antiepileptic treatment.
This study has been approved by the Ethic Committee in september 2004 (CCPPRB BICETRE, promotion of ASSISTANCE PUBLIQUE - HOPITAUX de PARIS).
|Study Type :||Observational|
|Actual Enrollment :||52 participants|
|Official Title:||Anatomical and Functional MRI Study of Episodic Memory in Epileptic Compared to Normal Children|
|Study Start Date :||October 2005|
|Actual Primary Completion Date :||February 2009|
|Actual Study Completion Date :||February 2009|
Behavioral: Study of memory using MRI
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00242905
|Service Hospitalier Frédéric Joliot (SHFJ)|
|Orsay, France, 91400|
|Paris, France, 75015|
|Principal Investigator:||Catherine CHIRON, MD,PhD||Assistance Publique - Hôpitaux de Paris|