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ClinicalTrials.gov Identifier: NCT00239096
Recruitment Status : Unknown
Verified October 2005 by Odense University Hospital. Recruitment status was: Recruiting
The purpose of this study is to determine whether losartan, an angiotensin II blocker prevents the sodium retention in patients with liver cirrhosis and by that reduces the fluid retention. Moreover is the purpose to asses whether losartan is antifibrotic.
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Layout table for eligibility information
Ages Eligible for Study:
18 Years to 70 Years (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
The presence of cirrhosis in a liver biopsy; or, in the absence of histology, clinical and laboratory evidence of cirrhosis combined with years of excessive alcohol intake.
Age 18-70 years
Cirrhosis due to alpha1-antitrypsin deficiency, viral hepatitis or autoimmunity.
Renal disease evidenced by proteinuria > 0,5 g/day.
Cancer or disease other than cirrhosis expected to limit life expectancy to < 5 years.