Ethyl-EPA Treatment of Prodromal Patients

This study has been completed.
Information provided by (Responsible Party):
Yale University Identifier:
First received: March 6, 2008
Last updated: May 21, 2014
Last verified: May 2014
This is an open-label trial of an omega-3 fatty acid for symptoms of the schizophrenia prodrome.

Condition Intervention Phase
Schizophrenia Prodrome
Drug: ethyl-eicosapentaenoic acid
Phase 2
Phase 3

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Ethyl-EPA Treatment of Prodromal Patients

Resource links provided by NLM:

Further study details as provided by Yale University:

Primary Outcome Measures:
  • conversion to psychosis [ Time Frame: one year ] [ Designated as safety issue: No ]

Enrollment: 7
Study Start Date: September 2001
Study Completion Date: August 2005
Primary Completion Date: August 2005 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: A Drug: ethyl-eicosapentaenoic acid
2 mg per day
Other Name: ethyl-EPA, an omega-3 fatty acid


Ages Eligible for Study:   14 Years to 35 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • meets criteria for schizophrenia prodrome

Exclusion Criteria:

  • any lifetime antipsychotic treatment
  Contacts and Locations
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Please refer to this study by its identifier: NCT00634361

Sponsors and Collaborators
Yale University
Principal Investigator: Scott W Woods, MD Yale University
  More Information

Responsible Party: Yale University Identifier: NCT00634361     History of Changes
Obsolete Identifiers: NCT00237835
Other Study ID Numbers: LA01.03.0011 
Study First Received: March 6, 2008
Last Updated: May 21, 2014
Health Authority: United States: Food and Drug Administration processed this record on May 23, 2016