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Evaluation of Topical Antipsoriatics in the Psoriasis Plaque Test

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00236171
First Posted: October 12, 2005
Last Update Posted: June 8, 2010
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
Technische Universität Dresden
  Purpose
The purpose of this study is to evaluate the efficacy of the topical therapies Protopic and Advantan as well as their combination against placebo in a Psoriasis Plaque Test

Condition Intervention
Psoriasis Vulgaris Drug: Protopic, Advantan Procedure: Blood and Urine Test Procedure: coherence tomography

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Single Group Assignment
Masking: Triple (Participant, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Evaluation of Topical Antipsoriatics in the Psoriasis Plaque Test

Resource links provided by NLM:


Further study details as provided by Technische Universität Dresden:

Primary Outcome Measures:
  • sum score of psoriasis plaque tests on day 11

Secondary Outcome Measures:
  • 20-MHz-ultrasound and OCT on day 11

Enrollment: 14
Study Start Date: September 2004
Study Completion Date: June 2010
Primary Completion Date: April 2006 (Final data collection date for primary outcome measure)
Detailed Description:
daily psoriasis plaque tests for two weeks and optical coherence tomography (OCT) and 20-MHz-ultrasound on day 0 and day 11, 10 days post end of treatment and 20 days post end of treatment
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Patients older than 18 Years
  • Negative urine pregnancy test
  • Written informed consent
  • Good compliance

Exclusion Criteria:

  • Patients less than 18 years
  • Pregnant patients
  • Patients with renal insufficiency, liver diseases
  • Patients who received systemic antipsoriatic treatment or UV treatment less than 4 weeks prior to study
  • Patients who used topical antipsoriatics within two weeks prior to study
  • Immunosuppressed Patients
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00236171


Locations
Germany
Technische Universität Dresden
Dresden, Sachsen, Germany, 0351
Sponsors and Collaborators
Technische Universität Dresden
Investigators
Principal Investigator: Gottfried Wozel, Professor Technische Universität Dresden
  More Information

Responsible Party: Gottfried Wozel, MD, Technical University Dresden
ClinicalTrials.gov Identifier: NCT00236171     History of Changes
Other Study ID Numbers: ETAPSO
First Submitted: October 4, 2005
First Posted: October 12, 2005
Last Update Posted: June 8, 2010
Last Verified: June 2010

Keywords provided by Technische Universität Dresden:
topical therapy
Psoriasis Plaque Test

Additional relevant MeSH terms:
Psoriasis
Skin Diseases, Papulosquamous
Skin Diseases