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Efficacy of Naltrexone Treatment as Augmentation to SSRI in OCD Patients

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ClinicalTrials.gov Identifier: NCT00234689
Recruitment Status : Completed
First Posted : October 7, 2005
Last Update Posted : January 30, 2008
Sponsor:
Information provided by:
Sheba Medical Center

Brief Summary:
Assessing the efficacy of Naltrexone as augmentation to SSRI in patients with OCD

Condition or disease Intervention/treatment Phase
Obsessive Compulsive Disorder Drug: Naltrexone Not Applicable

Study Type : Interventional  (Clinical Trial)
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Double
Study Start Date : January 2002
Actual Primary Completion Date : December 2004
Actual Study Completion Date : December 2004

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Ages Eligible for Study:   18 Years to 65 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Diagnosis of OCD
  • Treatment with SSRI for at least 10 weeks with no response

Exclusion Criteria:

  • Suffering from any medical condition
  • treatment with opiates
  • chronic use of drugs
  • Hepatitis or other liver related diseases
  • Incapability to sign an informed consent

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To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00234689


Locations
Israel
Chaim Sheba Medical Center
Ramat-Gan, Israel, 52621
Sponsors and Collaborators
Sheba Medical Center
Investigators
Principal Investigator: Joseph Zohar, MD Tel Aviv University
Study Chair: Revital Amiaz, MD Tel Aviv University

Responsible Party: Prof. Joseph Zohar, Chaim Sheba Medical Center
ClinicalTrials.gov Identifier: NCT00234689     History of Changes
Other Study ID Numbers: SHEBA-99-1897-JZ-CTIL
First Posted: October 7, 2005    Key Record Dates
Last Update Posted: January 30, 2008
Last Verified: January 2008

Additional relevant MeSH terms:
Compulsive Personality Disorder
Obsessive-Compulsive Disorder
Personality Disorders
Mental Disorders
Anxiety Disorders
Naltrexone
Narcotic Antagonists
Physiological Effects of Drugs
Sensory System Agents
Peripheral Nervous System Agents