Studying the Analgesic Mechanism of the "Cough-Trick"

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00233844
Recruitment Status : Completed
First Posted : October 6, 2005
Last Update Posted : October 6, 2005
Information provided by:
University Medicine Greifswald

Brief Summary:
The aim of the trial is to study the possible mechanism of the pain reducing effect of CT at peripheral venipuncture

Condition or disease Intervention/treatment Phase
Pain Acute Pain Venipuncture Procedure: Venipuncture with "cough-trick" Phase 2

Study Type : Interventional  (Clinical Trial)
Enrollment : 21 participants
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single
Primary Purpose: Treatment
Official Title: Studying the Analgesic Mechanism of the "Cough-Trick" - Randomized Crossover Volunteer Study
Study Start Date : February 2004

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Cough
U.S. FDA Resources

Primary Outcome Measures :
  1. Pain intensity measured on VAS-100 scale

Secondary Outcome Measures :
  1. Heart rate, arterial pressure, hand withdrawal, sweating

Information from the National Library of Medicine

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Ages Eligible for Study:   20 Years to 35 Years   (Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  1. Male volunteers aged 20-40 years, height 165-190 cm.
  2. Physical status I according to American Society of Anesthesiologists (ASA) classification.
  3. Straight run of the vein on the dorsum of the non-dominant hand at least 4 cm long and 3 mm thick
  4. No analgesics, anticoagulants and/or antiplatelet agents, sedatives or alcohol

Exclusion Criteria:

  1. History of peripheral neuropathy
  2. Abnormal skin conditions (infection, scars, psoriasis, eczema)
  3. Unsuccessful venipuncture
  4. Inflamed site of VP within 1 week after VP

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00233844

Sponsors and Collaborators
University Medicine Greifswald
Principal Investigator: Taras I. Usichenko, Assistant Professor Anesthesiology and Intensive Care Medicine Department, Ernst Moritz Arndt University of Greifswald, Germany Identifier: NCT00233844     History of Changes
Other Study ID Numbers: III UV 82/03
First Posted: October 6, 2005    Key Record Dates
Last Update Posted: October 6, 2005
Last Verified: October 2005

Keywords provided by University Medicine Greifswald:
Acute pain
pain on venipuncture

Additional relevant MeSH terms:
Acute Pain
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms
Sensory System Agents
Peripheral Nervous System Agents
Physiological Effects of Drugs