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Studying the Analgesic Mechanism of the "Cough-Trick"

This study has been completed.
Information provided by:
University Medicine Greifswald Identifier:
First received: October 5, 2005
Last updated: NA
Last verified: October 2005
History: No changes posted
The aim of the trial is to study the possible mechanism of the pain reducing effect of CT at peripheral venipuncture

Condition Intervention Phase
Pain Acute Pain Venipuncture Procedure: Venipuncture with "cough-trick" Phase 2

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single
Primary Purpose: Treatment
Official Title: Studying the Analgesic Mechanism of the "Cough-Trick" - Randomized Crossover Volunteer Study

Resource links provided by NLM:

Further study details as provided by University Medicine Greifswald:

Primary Outcome Measures:
  • Pain intensity measured on VAS-100 scale

Secondary Outcome Measures:
  • Heart rate, arterial pressure, hand withdrawal, sweating

Estimated Enrollment: 21
Study Start Date: February 2004

Ages Eligible for Study:   20 Years to 35 Years   (Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  1. Male volunteers aged 20-40 years, height 165-190 cm.
  2. Physical status I according to American Society of Anesthesiologists (ASA) classification.
  3. Straight run of the vein on the dorsum of the non-dominant hand at least 4 cm long and 3 mm thick
  4. No analgesics, anticoagulants and/or antiplatelet agents, sedatives or alcohol

Exclusion Criteria:

  1. History of peripheral neuropathy
  2. Abnormal skin conditions (infection, scars, psoriasis, eczema)
  3. Unsuccessful venipuncture
  4. Inflamed site of VP within 1 week after VP
  Contacts and Locations
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Please refer to this study by its identifier: NCT00233844

Sponsors and Collaborators
University Medicine Greifswald
Principal Investigator: Taras I. Usichenko, Assistant Professor Anesthesiology and Intensive Care Medicine Department, Ernst Moritz Arndt University of Greifswald, Germany
  More Information Identifier: NCT00233844     History of Changes
Other Study ID Numbers: III UV 82/03
Study First Received: October 5, 2005
Last Updated: October 5, 2005

Keywords provided by University Medicine Greifswald:
Acute pain
pain on venipuncture

Additional relevant MeSH terms:
Acute Pain
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms
Sensory System Agents
Peripheral Nervous System Agents
Physiological Effects of Drugs processed this record on August 18, 2017