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Spread of Dermatophytes Among Families

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ClinicalTrials.gov Identifier: NCT00233493
Recruitment Status : Unknown
Verified November 2004 by University Hospitals Cleveland Medical Center.
Recruitment status was:  Recruiting
First Posted : October 5, 2005
Last Update Posted : October 5, 2005
Sponsor:
Collaborator:
Novartis
Information provided by:
University Hospitals Cleveland Medical Center

Brief Summary:
The objective is to demonstrate person-to-person spread of dermatophytes of the skin and nails among family members, as measured by fungal culture and DNA typing of the dermatophytes isolated.

Condition or disease
Onychomycosis Tinea Pedis

Detailed Description:
Enrolled families consist of at least two members over the age of 14. Once the index person is examined and a dermatophyte is isolated from either toenail or foot scale, other family members are examined and cultured. All dermatophyte isolates obtained from each family unit are compared using DNA typing and restriction length polymorphism (RFLP) to determine whether family members share the same organism or were infected by an outside source.

Study Type : Observational
Enrollment : 150 participants
Observational Model: Defined Population
Observational Model: Natural History
Time Perspective: Longitudinal
Time Perspective: Prospective
Official Title: Demonstration of the Spread of Dermatophytes Through Casual Contact Among Family Household Members
Study Start Date : March 2005
Study Completion Date : February 2006




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Ages Eligible for Study:   14 Years and older   (Child, Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria: positive dermatophyte culture

Exclusion Criteria:

  • use of antifungal agents, either oral or topical

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00233493


Contacts
Contact: Mahmoud A Ghannoum, PhD 216-844-8580 mag3@case.edu
Contact: Nancy Isham, BA 216-983-3093 nancy.isham@uhhs.com

Locations
United States, Ohio
Neil Korman, MD Recruiting
Cleveland, Ohio, United States, 44106
Contact: ZsaZsa Hann    216-844-5899    zsazsa.hann@uhhs.com   
Sponsors and Collaborators
University Hospitals Cleveland Medical Center
Novartis
Investigators
Principal Investigator: Mahmoud A Ghannoum, PhD Center for Medical Mycology, University Hosp. of Cleveland

ClinicalTrials.gov Identifier: NCT00233493     History of Changes
Other Study ID Numbers: CSFO327KUS16
First Posted: October 5, 2005    Key Record Dates
Last Update Posted: October 5, 2005
Last Verified: November 2004

Keywords provided by University Hospitals Cleveland Medical Center:
dermatophytes

Additional relevant MeSH terms:
Onychomycosis
Tinea Pedis
Tinea
Dermatomycoses
Skin Diseases, Infectious
Infection
Mycoses
Nail Diseases
Skin Diseases
Foot Dermatoses
Foot Diseases
Pruritus
Skin Manifestations
Signs and Symptoms