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Case Notes Review on Patients With Hereditary Haemorrhagic Telangiectasia

This study is currently recruiting participants.
Verified August 2008 by Imperial College London
Sponsor:
ClinicalTrials.gov Identifier:
NCT00230685
First Posted: October 3, 2005
Last Update Posted: May 29, 2015
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.
Collaborator:
The Margaret Hayton HHT Fund
Information provided by (Responsible Party):
Imperial College London
  Purpose
The Hammersmith Hospital provides a clinical service for patients with Hereditary haemorrhagic telangiectasia and pulmonary arteriovenous malformations that is unique in the United Kingdom. Measurements obtained as part of standard clinical practice that has evolved since 1985 allow us to assess whether particular groups of individuals that we see are more prone to recognised complications such as strokes, brain abscesses, pregnancy related complications or pulmonary hypertension. We hypothesise that certain clinical characteristics will predict the susceptibility of individuals to particular complications.

Condition
Telangiectasia, Hereditary Hemorrhagic

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Hammersmith Hospital Patients With Pulmonary Arteriovenous Malformations (PAVMs) and Hereditary Haemorrhagic Telangiectasia

Resource links provided by NLM:


Further study details as provided by Imperial College London:

Primary Outcome Measures:
  • Stroke [ Time Frame: Prospective ]
  • Venous thromboemboli (VTE) [ Time Frame: Prospective ]

Estimated Enrollment: 500
Study Start Date: January 2000
Estimated Study Completion Date: January 2018
Estimated Primary Completion Date: January 2018 (Final data collection date for primary outcome measure)
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients referred to the hereditary haemorrhagic telangiectasia clinical service at Hammersmith Hospital, imperial College Healthcare NHS Trust
Criteria

Inclusion Criteria:

  • Patients attending Hammersmith Hospital

Exclusion Criteria:

  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00230685


Contacts
Contact: Claire L Shovlin 0208 383 1000 c.shovlin@imperial.ac.uk

Locations
United Kingdom
Respiratory Medicine, Hammersmith Hospital Recruiting
London, United Kingdom, W12 0NN
Contact: Claire L Shovlin       c.shovlin@imperial.ac.uk   
Principal Investigator: Claire L Shovlin         
Sponsors and Collaborators
Imperial College London
The Margaret Hayton HHT Fund
Investigators
Principal Investigator: Claire L Shovlin Imperial College London
  More Information

Publications:

Responsible Party: Imperial College London
ClinicalTrials.gov Identifier: NCT00230685     History of Changes
Other Study ID Numbers: IC/CLS2
First Submitted: September 29, 2005
First Posted: October 3, 2005
Last Update Posted: May 29, 2015
Last Verified: August 2008

Keywords provided by Imperial College London:
Pulmonary arteriovenous malformations

Additional relevant MeSH terms:
Arteriovenous Malformations
Arteriovenous Fistula
Vascular Malformations
Cardiovascular Abnormalities
Congenital Abnormalities
Telangiectasis
Telangiectasia, Hereditary Hemorrhagic
Vascular Diseases
Cardiovascular Diseases
Hemostatic Disorders
Hemorrhagic Disorders
Hematologic Diseases
Vascular Fistula
Fistula
Pathological Conditions, Anatomical