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Trial record 5 of 11 for:    "Atrioventricular septal defect"

Optimal Timing for Repair of Left to Right Shunt Lesions

This study has been terminated.
(sufficient data was collected)
Sponsor:
ClinicalTrials.gov Identifier:
NCT00229827
First Posted: September 30, 2005
Last Update Posted: March 16, 2012
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
Children's Healthcare of Atlanta
  Purpose
The purpose of this study is to determine the optimal timing for repair of left-to-right shunt lesions such as ventricular septal defects and atrioventricular canals.

Condition
Ventricular Septal Defects Persistent Common Atrioventricular Canal

Study Type: Observational
Study Design: Time Perspective: Retrospective
Official Title: Optimal Timing for Repair of Left-to-Right Shunt Lesions

Resource links provided by NLM:


Further study details as provided by Children's Healthcare of Atlanta:

Estimated Enrollment: 200
Study Start Date: May 2005
Study Completion Date: August 2007
Detailed Description:
In the past, children with left-to-right shunt lesions such as ventricular septal defects and atrioventricular canal defects were palliated with a pulmonary artery band. This prevented injury to the pulmonary vasculature while the child grew to a size where complete repair could be undertaken. With the improvements in surgical technique and critical care, there is a push to do a primary complete repair for these defects at younger and younger ages. These operations should be delayed as long as possible to allow for growth but not so long that there is unnecessary heart failure and medication requirements. The primary aim is to determine the optimal timing for repair of left-to-right shunt lesions such as ventricular septal defects and atrioventricular canals. The secondary aim is to define the criteria for failing medical anti-congestive heart failure therapy. This study will be conducted through a retrospective chart review.
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Patients in the congenital surgery database

  • Patients who have undergone repair of ventricular septal defects
  • Patients who have undergone repair of atrioventricular canal defects
Criteria

Inclusion Criteria:

  • Patients in the congenital surgery database
  • Patients who have undergone repair of ventricular septal defects
  • Patients who have undergone repair of atrioventricular canal defects
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00229827


Locations
United States, Georgia
Children's Healthcare of Atlanta at Egleston
Atlanta, Georgia, United States, 30322
Sponsors and Collaborators
Children's Healthcare of Atlanta
Investigators
Principal Investigator: Brian Kogon, MD Emory University
  More Information

ClinicalTrials.gov Identifier: NCT00229827     History of Changes
Other Study ID Numbers: 05-092
First Submitted: September 13, 2005
First Posted: September 30, 2005
Last Update Posted: March 16, 2012
Last Verified: May 2007

Keywords provided by Children's Healthcare of Atlanta:
pediatric health
cardiac
pediatric population
congenital heart surgery
left to right shunt lesions
heart surgery
Atrioventricular canal defects

Additional relevant MeSH terms:
Heart Septal Defects
Heart Septal Defects, Ventricular
Endocardial Cushion Defects
Mitral Valve Insufficiency
Heart Defects, Congenital
Cardiovascular Abnormalities
Cardiovascular Diseases
Heart Diseases
Congenital Abnormalities
Heart Valve Diseases