Study of Genetic Differences in People With Depression (Genetics)
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ClinicalTrials.gov Identifier: NCT00229463
: September 29, 2005
Last Update Posted
: November 18, 2016
University of California, Los Angeles
Information provided by (Responsible Party):
Andrew F. Leuchter, University of California, Los Angeles
The purpose of this study is to identify genes involved in depression. Specifically, the investigators will analyze some genes that may be related to whether or not a person responds to antidepressant medication. This project is part of basic scientific research to increase understanding of the role of genetic influences in psychological and mental processes involved in the response to treatment for depression.
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Ages Eligible for Study:
18 Years to 75 Years (Adult, Senior)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Patients will be recruited from previous studies conducted at the Laboratory of Brain, Behavior, and Pharmacology, where subjects' response to treatment has already been determined. This strategy offers the advantage that no new subjects need to be enrolled in placebo-controlled treatment studies.
History of Unipolar Major Depression
Control subjects must be healthy normal adults
Subjects with mood symptoms that are not severe enough to qualify for MDD
Subjects with any active medical illness that may be related to ongoing mood disorder
Normal subjects must be free from: a psychiatric diagnosis, substance abuse, a history of seizure disorder, and any serious medical illness