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Culturally Sensitive Collaborative Treatment for Depressed Chinese Americans

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00227929
First Posted: September 28, 2005
Last Update Posted: December 10, 2013
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Collaborator:
National Institute of Mental Health (NIMH)
Information provided by (Responsible Party):
Albert Yeung, Massachusetts General Hospital
  Purpose
This study will evaluate the effectiveness of culturally sensitive treatment versus regular care in treating depressed Chinese Americans.

Condition Intervention
Depression Procedure: Care Management

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Effectiveness of Culturally Sensitive Collaborative Treatment (CSCT) of Depressed Chinese Americans in Primary Care

Resource links provided by NLM:


Further study details as provided by Albert Yeung, Massachusetts General Hospital:

Primary Outcome Measures:
  • Symptoms of depression; measured at Weeks 2, 6, 10, 14, 18, 22, and 24

Secondary Outcome Measures:
  • Adherence to clinic visits with the primary care physicians; measured at Weeks 2, 6, 10, 14, 18, 22, and 24
  • Quality of life; measured at Weeks 2, 6, 10, 14, 18, 22, and 24
  • Adherence to medication treatment; measured at Weeks 2, 6, 10, 14, 18, 22, and 24
  • Adverse events; measured at Weeks 2, 6, 10, 14, 18, 22, and 24

Estimated Enrollment: 120
Study Start Date: July 2003
Study Completion Date: June 2008
Primary Completion Date: September 2007 (Final data collection date for primary outcome measure)
Detailed Description:

Depression is a complex illness that impacts an individual's thoughts, behavior, mood, and physical health. Research has shown that many Asian Americans with depression do not complain about their symptoms or seek treatment, which has lead to an under-recognition of depression in this population. Furthermore, even when a primary care physician does diagnose depression in an Asian American, adequate treatment does not often follow. There is a clear need to understand the cultural reasons for why treatment is not sought out by Asian Americans. There is also a need for developing new treatments that specifically target the Asian American population. Offering culturally sensitive therapies combined with traditional medical care may make depressed Asian Americans more comfortable in seeking treatment for their illness. Culturally Sensitive Collaborative Treatment (CSCT) is a comprehensive approach to treating depression. It incorporates consultation with a culturally trained psychiatrist, medical treatment provided by a primary care provider, and care management provided by a bilingual and bicultural care manager. The purpose of this study is to evaluate the effectiveness of CSCT versus traditional medical care for the treatment of depression in Chinese Americans.

This 24-week study will enroll depressed Chinese Americans. Potential participants will be interviewed in primary care clinics to screen for depression. Once enrolled, all participants will attend a consultation with a psychiatrist trained in cultural sensitivity to introduce the concept and treatment of depression. Participants will then be randomly assigned to either CSCT or standard care. Both groups of participants will receive regular care from their primary care provider, but the CSCT group will also meet with a bilingual and bicultural care manager to learn how to fully manage their depression. Outcome measurements will include symptoms of depression; adherence to appointments with primary care providers; adherence to medication treatment; and adverse events. All measurements will be assessed during follow-up phone calls at Weeks 2, 6, 10, 14, 18, 22, and 24.

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Chinese ethnicity
  • Currently depressed as determined by a total score of at least 16 on the CBCI scale
  • Speaks and understands English or Chinese (including Mandarin, Cantonese, and Taiwanese dialect)
  • Willing to participate in follow-up phone calls

Exclusion Criteria:

  • Currently at risk for suicide
  • Current unstable medical illness
  • Current clinical or laboratory evidence of hypothyroidism
  • Diagnosed with any of the following in addition to depression: organic mental disorder; schizophrenia; delusional disorder; psychotic disorder; bipolar disorder; mood congruent or mood incongruent psychotic features
  • History of treatment by a psychiatrist within 4 months of study entry
  • History of alcohol or substance abuse within 1 year of study entry
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00227929


Locations
United States, Massachusetts
South Cove Community Health Center
Boston, Massachusetts, United States, 02111
Sponsors and Collaborators
Massachusetts General Hospital
National Institute of Mental Health (NIMH)
Investigators
Principal Investigator: Albert Yeung, MD Massachusetts General Hospital
  More Information

Responsible Party: Albert Yeung, Staff Psychiatrist, Massachusetts General Hospital
ClinicalTrials.gov Identifier: NCT00227929     History of Changes
Other Study ID Numbers: K23MH067085 ( U.S. NIH Grant/Contract )
DSIR 8K-RTSE
First Submitted: September 26, 2005
First Posted: September 28, 2005
Last Update Posted: December 10, 2013
Last Verified: December 2013

Keywords provided by Albert Yeung, Massachusetts General Hospital:
Major Depressive Disorder
MDD